Apple Tree Partners

Apple Tree Partners (ATP) is a distinguished venture capital firm focused on life sciences, founded in 1999 by Dr. Seth Harrison. With offices in New York, San Francisco, and Cambridge, ATP has committed $2.9 billion in capital, making it one of the key players in biotech venture investing. The firm’s approach is unique in that it both creates and invests in companies, often starting from early-stage scientific ideas or asset spinouts from other companies. ATP provides flexible capital and strategic support to foster the development of science-driven enterprises. The firm is involved in every stage of a company’s life cycle, from seed investments to IPO and beyond. Notably, ATP has been instrumental in launching over 30 life sciences companies, of which 19 have gone public or been acquired. Some successful portfolio companies include Chinook Therapeutics, Akero Therapeutics, and Stoke Therapeutics​. In addition to financial backing, ATP brings operational expertise to its portfolio companies, helping them navigate clinical trials, regulatory processes, and market entry strategies. The firm has pioneered advancements in fields such as oncology, metabolic diseases, and inflammatory disorders, combining deep scientific understanding with entrepreneurial rigor. ATP’s investments, including its recent creation of Deep Apple Therapeutics, exemplify its commitment to using cutting-edge technologies like AI and machine learning to accelerate drug discovery and deliver life-changing therapies.