Ascension Ventures

Ascension Ventures is a strategic healthcare-focused venture capital firm based in St. Louis, Missouri. Launched in 2001 by Ascension, it manages over $1 billion in assets across five funds. The firm strategically invests in early to late-stage companies within healthcare services, health technology, and medical devices. Its unique approach connects more than 450 healthcare providers, creating an ecosystem that enables startups to directly engage with health system executives, driving solutions that address complex healthcare challenges. Ascension Ventures’ portfolio includes companies like Olive (an AI platform for healthcare administration), EBR Systems, and GetWellNetwork, reflecting its emphasis on technology that enhances clinical outcomes, patient experience, and operational efficiency. The firm typically invests between Series A and B rounds, with capital sizes ranging from $10 to $20 million per company, often seeking board seats or observer rights to guide their portfolio firms. The firm is distinguished by its close ties to 13 major health systems, which represent a network of over 580,000 healthcare professionals. This strategic positioning allows Ascension Ventures not only to provide funding but also to facilitate partnerships and scale innovations that improve healthcare delivery across the United States.