Prefix Capital

Prefix Capital is a San Francisco-based venture capital firm founded in 2019, focused on early-stage investments in deep-tech companies. The firm targets foundational technologies, with a particular emphasis on Big Data, AI/ML (Artificial Intelligence/Machine Learning), CloudTech, and enterprise software. Prefix Capital typically invests in Seed to Series B rounds, providing critical early capital to startups that are developing cutting-edge solutions with long-term potential. The firm’s portfolio includes notable companies like Symmetry Systems and VIA, which are leaders in enterprise infrastructure and environmental technology, respectively. Prefix Capital has a strong track record, with three unicorns in its portfolio: Ample, Tractable, and Diamond Foundry, reflecting its knack for identifying and nurturing high-growth potential ventures. Managed by a small, focused team led by Owen Van Natta, Prefix Capital is known for its hands-on approach, helping startups navigate the challenges of scaling while staying true to their technical and market-driven roots. The firm’s investment strategy is not just about providing capital but also about partnering with founders to turn visionary ideas into successful businesses​.