3x5 Partners

3x5 Partners is a Portland, Oregon-based venture capital firm that focuses on investments in companies developing solutions for global health and climate challenges. Founded in 2011 by Tony Arnerich and Nicholas Walrod, the firm has raised over $400 million across multiple funds, including their most recent $100 million Fund III. 3x5 Partners primarily invests in late-stage (Series A/B) ventures within sectors such as biotechnology, medical devices, diagnostics, and clean technology. The firm is known for its commitment to long-term partnerships, often leading early investment rounds and providing significant follow-on funding. Notable investments include companies like Fervo Energy, Arch Oncology, and Smart Wires, all of which align with their mission to create meaningful social and environmental impact. 3x5 Partners differentiates itself by focusing on capital-intensive, high-impact ventures that are often overlooked by traditional venture capital firms. They take an active role in the companies they invest in, serving as board members and strategic partners to guide these ventures through critical growth stages. The firm's leadership team, which includes seasoned investors like Joe Biller and David Yeh, is deeply experienced in both impact investing and venture capital, ensuring that they not only generate strong returns for their investors but also contribute to solving some of the world's most pressing problems.