Asset Management Ventures

Asset Management Ventures (AMV) is a Palo Alto-based venture capital firm founded in 1965 by Pitch Johnson, one of Amgen's co-founders — making it one of the longest continuously operating VC firms in Silicon Valley. The firm specializes in early-stage investments in digital health, technology, and life sciences, and raised its fifth and largest fund at $150 million in 2020. Partners Skip Fleshman and Lou Lange lead the current investment team, which combines scientific, engineering, and medical expertise with decades of investing experience. With 152 investments and 29 exits, AMV's historical portfolio includes Amgen itself, Tandem Computer, and Applied BioSystems — foundational companies in their respective industries. The current portfolio includes Reify Health, Evidation Health, Lark, Twist Bioscience (TWST), Freenome, Welldoc, ViewPoint Therapeutics, Aavia, and 3T Biosciences, reflecting AMV's sustained focus on health technology and life sciences innovation. The firm leads rounds and deploys $1 million to $15 million across seed through Series B stages. AMV's six-decade track record is its most distinctive asset: the firm has seen multiple complete technology and healthcare cycles, giving the investment team a depth of pattern recognition and investor network that newer funds cannot replicate. The founding connection to Amgen also provides an ongoing cultural orientation toward building enduring life sciences companies rather than optimizing for short-cycle exits — an orientation that informs how AMV partners with founders over the long arc of company development.