Define Ventures

Define Ventures is a premier early-stage venture capital firm, singularly focused on investing in digital health companies. With a keen eye for transformative potential, Define Ventures partners with innovative entrepreneurs to reshape the healthcare landscape. Their portfolio features notable investments such as Blackbird Health, which is revolutionizing pediatric mental health, and Lightship, a pioneer in decentralized clinical trials. Define Ventures operates primarily within the digital health sector, focusing on business models that integrate technology and healthcare to create scalable solutions. Geographically, they concentrate their efforts within the United States, fostering close relationships with startups that promise substantial impact in the national healthcare system. The firm’s strategy centers on leading early-stage funding rounds, including incubation, seed, Series A, and Series B stages. Define Ventures is renowned for their hands-on approach, providing not just capital but also strategic guidance and industry expertise to help their portfolio companies thrive. The team is led by industry veterans like Lynne Chou O'Keefe, the founder and managing partner, whose vision drives the firm's success. Other key members include A.G. Breitenstein and Frank Williams, both of whom bring extensive experience in healthcare and digital innovation. Define Ventures has recently closed $460 million across Fund III and an Opportunities Fund, cementing its position as a significant player in digital health investment.