OSF Ventures

OSF Ventures is the corporate venture capital arm of OSF HealthCare, a 15-hospital nonprofit integrated health system operating across Illinois and Michigan. Founded in 2015 and headquartered in Peoria, Illinois, OSF Ventures sits within OSF Innovation and invests financially, operationally, and strategically in healthcare companies whose technologies can improve patient outcomes, enhance patient experience, and reduce the cost of care. Mayank Taneja, Vice President of Venture Investments, leads a seven-person team across three successive fund vintages that have grown cumulative AUM to $250 million, anchored by Fund III, a $100 million vehicle launched in January 2022 with a thesis tilt toward alternative care modalities and healthcare workforce retention. The firm participates as a syndicate member at Series A through growth stages and has made approximately 37 investments spanning health information technology, medical devices, therapeutics, diagnostics, and technology-enabled care delivery. The portfolio has produced notable exits including Current Health (acquired by Best Buy in 2021), Health Catalyst (NASDAQ IPO in 2019), and SilverCloud Health (acquired by Amwell in 2021). Recent deployments include Hellocare.ai, Cala, ShiraTronics, Cardiosense ($15.1 million Series A for an AI heart disease biomarker platform), 410 Medical ($6.3 million Series B for pediatric sepsis), and Digital Diagnostics ($75 million Series B, autonomous AI diagnostics). OSF Ventures brings more than just capital to portfolio companies. Its status as an active operating health system means founders gain access to clinical validation environments, practitioner networks, and patient populations that can meaningfully accelerate regulatory and commercial timelines, making the fund a strategic partner in addition to a financial backer.