Biotech VC Funds

The Ambition Fund, founded by Tanya Sam, is a venture capital firm dedicated to funding women and underrepresented minority entrepreneurs. Based in Atlanta, Georgia, the fund focuses on early-stage and seed-stage investments across diverse sectors, including consumer products, media, and technology. Its mission is to provide opportunities for founders who traditionally face barriers in accessing venture capital, promoting diversity and inclusion within the startup ecosystem​. Tanya Sam, a tech entrepreneur and television personality known for her role on The Real Housewives of Atlanta, leads the fund with a deep commitment to fostering innovation and economic empowerment. In addition to her work with The Ambition Fund, she is the Director of Partnerships at TechSquare Labs and co-leads the Ascend Atlanta program, which has helped over 60 companies, collectively generating over $100 million in revenue. Her strong background in tech and business development has positioned her as a key advocate for underrepresented founders. The Ambition Fund actively seeks out innovative startups with high growth potential and social impact. The fund typically makes investments ranging from $100,000 to $500,000. It has also launched initiatives such as the Business Battle Pitch Competition, which provides an interactive platform for minority entrepreneurs to pitch their ideas and secure fundin. By providing capital, mentorship, and strategic support, The Ambition Fund aims to elevate a new generation of diverse founders and drive meaningful change in the venture capital landscape.

TCG, formerly known as The Chernin Group, is a venture capital firm specializing in consumer businesses across various industries, from media to health and wellness, gaming, and consumer finance. Notable investments include Headspace, Barstool Sports, Crunchyroll, and Food52. TCG's strategy revolves around identifying strong consumer brands with passionate fan bases and solid business models, often in direct-to-consumer and subscription-based businesses. They aim to partner with management teams that have already established great brands but need assistance in scaling further​. Geographically, TCG focuses on investments in North America, with offices in Los Angeles, San Francisco, and New York. The firm typically leads rounds, leveraging its extensive network and expertise to provide significant operational support and access to capital. They recently closed a new fund with over $700 million in commitments, showcasing their robust financial backing and commitment to future investments. The team comprises seasoned professionals like Peter Chernin, Jesse Jacobs, and Mike Kerns, who bring a wealth of experience from their previous roles in major companies like News Corp and Yahoo!. This diverse team shares a common drive and curiosity, crucial for identifying and nurturing the next big consumer trends​. For startups looking to approach TCG, it's best to highlight how your company aligns with evolving consumer behaviors and demonstrates potential for strong brand identity and a loyal customer base. They value founders who have done the hard work in building their brands and are ready to scale with the right strategic support.

The Community Fund is a $5 million early-stage venture capital fund launched in 2020, focused on investing in community-driven companies. Co-founded by Lolita Taub, the fund believes that building strong, vibrant communities can create a competitive advantage for startups. The fund typically invests at the pre-seed and seed stages, aiming to support founders who are leveraging community as a core element of their business models. The Community Fund has backed over 40 companies across various sectors, including health, wellness, and tech. Some of its notable investments include Elektra Health and Kindra, both of which focus on empowering communities through innovative health solutions. The fund operates with a diverse team of investment partners, ensuring broad expertise and support for the startups they work with. With a strong mission to drive inclusive innovation, The Community Fund prioritizes working with underrepresented founders, ensuring that community-building is not only a business strategy but also a tool for social impact. Their investment approach goes beyond financial backing, offering mentorship, strategic guidance, and access to a vast network of industry experts to help startups succeed.

E14 Fund is an MIT-affiliated venture capital firm focused on supporting deep-tech startups emerging from the MIT community. Established in 2013 and rooted in the MIT Media Lab, the fund specializes in companies that are addressing critical global challenges through breakthrough science and engineering. E14 Fund invests in early-stage startups, typically from pre-seed to Series A, with a focus on industries such as robotics, artificial intelligence, quantum computing, and synthetic biology. Some notable investments include Formlabs, a leader in 3D printing technology, and Overjet, a pioneer in AI-powered dental care solutions. The fund is more than just a capital provider; it acts as a strategic partner, helping founders transition from academic research to building scalable businesses. E14 leverages the vast MIT network to connect entrepreneurs with industry leaders, mentors, and technical resources that can help accelerate their growth. A significant portion of the firm’s profits is reinvested into MIT, highlighting its commitment to fostering long-term innovation within the university ecosystem. Led by managing partners Calvin Chin and Habib Haddad, E14 Fund works closely with founders to address both scientific and business challenges, providing hands-on support throughout their journey. The fund’s portfolio companies typically possess unique intellectual property and a clear path to market dominance, reflecting E14’s focus on ventures with transformative potential. By supporting startups from their earliest stages, E14 Fund plays a crucial role in translating groundbreaking MIT research into impactful, market-ready technologies.

Engine, founded by MIT in 2016, is a venture firm designed to support "Tough Tech" companies—those that tackle complex, science-based challenges in areas such as climate change, human health, and advanced systems. The firm provides more than just capital, offering infrastructure, labs, equipment, and a powerful network to help startups transition from groundbreaking research to commercial success. Engine focuses on companies that operate at the intersection of science and engineering, aiming to create transformative solutions for some of the world’s most pressing problems. The firm’s portfolio features notable companies like Commonwealth Fusion Systems, which is advancing fusion energy as a sustainable power source, and Boston Metal, a leader in decarbonizing steel production. These investments reflect Engine's commitment to technologies that promise to have a lasting impact on society and the environment. Led by Katie Rae, Engine's strategy centers on bridging the gap between research and commercialization by providing technical founders with the resources and networks they need to scale effectively. Engine's approach combines patient capital with operational support, helping entrepreneurs navigate the challenges of building in highly regulated and complex industries. Based in Cambridge, Massachusetts, Engine leverages its proximity to top-tier academic and research institutions to stay at the forefront of innovation. Through its integrated support system, Engine enables Tough Tech startups to accelerate their growth, with a long-term focus on reshaping industries and addressing critical global challenges..

The Fund VC, established in 2018, is a unique venture capital firm that operates a community-driven investment model. It focuses on early-stage startups across a variety of sectors including technology, consumer goods, and healthcare. The Fund VC operates through a network of micro-funds spread across different cities such as New York, Los Angeles, London, and Sydney, each managed by a group of local investors with deep expertise in their respective markets. The Fund VC has made notable investments in companies like Tia, a women’s health tech company; Parsley Health, a holistic health startup; and Bravely, a platform providing on-demand professional coaching. This portfolio reflects their commitment to backing innovative solutions that address significant market needs. The firm leverages its extensive network of founders, operators, and investors to provide not just capital but also mentorship and strategic support to its portfolio companies. This approach helps startups navigate early challenges and scale effectively. The Fund VC is particularly known for fostering a strong community among its portfolio companies, encouraging collaboration and shared growth​

The General Partnership (TheGP) is a venture capital firm that stands out for its unique "Sweat Equity" model, which combines both capital investment and hands-on operational support. Founded in 2022, TheGP focuses on partnering with early-stage startups, especially those in the pre-seed and seed stages, helping them achieve product-market fit and scale effectively. What makes TheGP distinctive is its deep involvement with portfolio companies. Beyond just financial investment, TheGP deploys its team of seasoned engineers, recruiters, designers, and product experts to work directly within startups. This "Sweat Equity" approach means that TheGP team members are embedded in the companies they invest in, often spending up to nine months helping build out teams, optimize product development, and refine go-to-market strategies. Their model has proven successful, leading to the launch of their second fund, TheGP II, with $300 million in committed capital. This fund will continue their mission of providing both capital and expert support to founders who value active partnership over mere financial backing.

The Helm is a New York City-based early-stage venture capital firm with a mission to invest in female-founded companies and redefine the venture landscape by focusing on gender-lens investing. Founded by Lindsey Taylor Wood, The Helm has become a prominent player in supporting women-led startups across various industries including healthcare, sustainability, and technology. Notable portfolio companies include Tia, a modern healthcare provider for women; Venus Aerospace, pushing the boundaries of hypersonic transportation; and Rebellyous Foods, revolutionizing plant-based meat production. The Helm’s investment strategy emphasizes identifying undervalued companies that demonstrate significant promise early on, ensuring they have the capital to achieve their potential. Their average check size varies, but they are known for leading funding rounds and maintaining active engagement with their portfolio companies. Startups seeking investment should highlight innovative solutions and robust business models that align with The Helm’s focus on female empowerment and sustainability. The team at The Helm includes Lindsey Taylor Wood, who leads the fund’s strategy and fundraising efforts; Julie Weber, COO and General Partner, with extensive experience in fund administration and operations; and Olivia Fleming, Partner, who directs the fund’s sustainability initiatives and angel investor network. This experienced team supports a diverse portfolio of over 20 companies and maintains a strong community of investors and founders committed to advancing female entrepreneurship.

The House Fund is a pre-seed and early-stage venture capital firm focused on investing in startups affiliated with UC Berkeley alumni, faculty, and students. Founded in 2016 and based in Berkeley, California, the fund has established itself as a cornerstone of the Berkeley startup ecosystem. Notable investments from The House Fund include PsiQuantum, Superhuman, Queenly, Flexport, and Anyscale, with a particular emphasis on artificial intelligence, software, and industrial applications. The fund's industry focus spans AI, software, human capital, and consumer technologies, leveraging Berkeley's rich talent pool to identify and nurture high-potential startups. Geographically, The House Fund primarily invests in the United States, with a strong concentration in the Bay Area. Their investment strategy involves leading or co-leading pre-seed and early-stage rounds, often with check sizes up to $2 million for early-stage and up to $1 million for pre-seed investments. The fund aims to be the first investor in promising startups, offering extensive support through their network and resources. The House Fund has been highly active, particularly in the AI sector, fostering a robust AI ecosystem at Berkeley. Their approach involves close collaboration with founders, providing not only capital but also strategic guidance and access to a network of seasoned entrepreneurs and industry experts. This hands-on support has been instrumental in the success of their portfolio companies.

Longevity Fund is a venture capital firm that focuses on extending healthy human lifespan through medical innovations. Established in 2013, the firm is dedicated to investing in biotech startups developing therapies to combat age-related diseases. The fund primarily supports early-stage companies, especially those pioneering treatments aimed at slowing or reversing the aging process. The firm has backed several significant players in the longevity field, including Unity Biotechnology, Spring Discovery, and Loyal. These companies are working on groundbreaking solutions in areas such as cellular senescence, AI-driven drug discovery, and tissue regeneration. The Longevity Fund also collaborates with age1, an accelerator designed to support founders working in this niche sector. Longevity Fund’s investment strategy is built around founder-led companies with a mission-driven approach. They believe the next generation of biotech leaders will be those who are passionate about fundamentally transforming medicine to extend life expectancy. The firm seeks startups that are not only scientifically innovative but also have a clear path toward FDA approvals and scalable business models. Based in San Francisco, Longevity Fund continues to push the boundaries of what is possible in healthcare, aiming to make age-related diseases a thing of the past and give individuals more control over the number of healthy years they can live.

Spartan Group is a leading venture capital and advisory firm focused on the digital asset space, with a strong presence in Singapore and Hong Kong. Specializing in blockchain and decentralized finance (DeFi), they invest across early to mid-stage companies. Their portfolio features high-profile projects such as Animoca Brands, Mysten Labs, and Unstoppable Domains, which have achieved unicorn status. Spartan’s deep expertise in Web3 and crypto markets positions them as a key player in helping projects scale. The firm has a clear focus on disruptive technologies, particularly blockchain, decentralized finance, and gaming ecosystems. They’ve led investment rounds in notable projects like LayerZero Labs and Synthetix, demonstrating their commitment to supporting innovations that redefine financial and digital systems. Spartan Group typically invests alongside other major players in the crypto space, including Binance and Animoca Brands. Their strategy involves not only providing capital but also offering strategic advice and access to their extensive network in the blockchain industry. Spartan’s leadership, including partners like Kelvin Koh and Melody He, has significant experience in both traditional finance and the emerging digital asset space. Their hands-on approach and deep sector knowledge make them an attractive partner for blockchain startups aiming to navigate the complex Web3 landscape. For startups seeking investment, Spartan Group prioritizes teams with strong technical expertise and projects that can demonstrate a clear path to market dominance in the decentralized economy.

The Venture Collective, founded in 2019 and headquartered in New York, focuses on early-stage investments in transformative technology and science-driven startups. The firm supports purpose-driven solutions across various sectors, including deep tech, climate tech, and biotech. TVC has made 44 investments, with notable portfolio companies such as Infogrid, HelixNano, Builder.ai, and Endpoint Health. Infogrid, an AI-powered platform for building management, and HelixNano, which leverages synthetic biology for mRNA therapeutics, are among TVC's significant investments. The firm co-invests with other prominent venture capital firms to bolster its portfolio companies with comprehensive support and strategic guidance. The leadership team includes Founding Partners Gina Kirsch and Nicholas Shekerdemian, along with a diverse group of principals and advisors who bring extensive experience from top-tier organizations like BlackRock and Franklin Templeton. TVC is dedicated to backing founders who tackle complex societal challenges, aiming to create substantial global impact through innovation.

TheVentureCity, founded in 2017, is a global early-stage venture capital firm focused on product-centric startups across the US, Europe, and Latin America. The firm manages over $150 million in assets, investing from pre-seed and seed stages up to Series A, with investment sizes ranging from $100,000 to $500,000. TheVentureCity's diverse portfolio includes companies such as Sidekick in financial services, Tiny Health in biotechnology, and Moonflow, a SaaS platform for debt collections. These investments highlight their commitment to sectors like AI/ML, cybersecurity, FinTech, and SaaS. Operating with an operator-led model, TheVentureCity provides both financial backing and strategic support to help startups scale globally. This approach has led to successful funding rounds and the growth of companies like Fixme Connect, BrandLovrs, and Plexigrid. Key team members, including founders Laura González-Estéfani and Clara Bullrich, leverage their extensive experience in technology investment and international scalability to drive the firm’s success and support portfolio companies effectively.

3KVC, also known as 3K Venture Capital, focuses on early-stage investments in innovative technology companies. Founded to address the financing needs of startups, 3KVC aims to support entrepreneurs by providing both capital and strategic guidance to help them scale and succeed in competitive markets. The firm has a diverse portfolio, investing in sectors such as software, healthcare, and consumer technology. 3KVC leverages the extensive industry experience of its team members, who bring a wealth of knowledge from various disciplines and a successful track record of previous ventures.

Third Nature Investments is a venture capital firm focused on systemic, impact-driven investments that aim to align human innovation with the preservation and restoration of Earth’s natural systems. Founded by Jason W. Ingle, who previously co-founded Closed Loop Capital, Third Nature leverages a decade of experience investing in agricultural technology and food system innovations. With Closed Loop Capital, Ingle backed pioneering companies in biological fertilizers, plant-based proteins, and fermentation technology, catalyzing billions in investor capital into these markets. Third Nature expands on this foundation by embracing an "earth systems" approach, targeting broader areas such as climate tech, sustainable packaging, and regenerative agriculture. The fund focuses on creating market-level transformations, rather than isolated, enterprise-level solutions, by examining the complex interdependencies between global ecosystems like oceans, forests, and the atmosphere. Its investments include companies such as Sway, a leader in sustainable packaging, and Atlantic Sea Farms, which focuses on aquaculture​. The firm operates with the belief that solving planetary challenges requires interconnected solutions, combining human ingenuity with natural restoration efforts. Third Nature not only invests in startups that work to decarbonize industries but also in those that actively regenerate ecosystems, positioning the firm as a major player in impact investing​. With a focus on systems-level change, Third Nature is redefining how venture capital can support both profitable growth and environmental stewardship.

Third Prime is an early-stage venture capital firm focusing on financial and industrial technology sectors. Established in 2016 by Keith Hamlin and Wes Barton, the firm leverages their extensive backgrounds in M&A law, private equity, and hedge funds to identify and invest in paradigm-shifting startups. Notable investments include companies such as Moonware, which automates aviation ground operations, and Paywatch, which offers financial wellness services in Asia. The firm prioritizes close partnerships with entrepreneurs, offering both capital and strategic guidance. With a keen eye for early insights and a commitment to optimizing outcomes for both founders and investors, Third Prime has built a diverse portfolio. This includes companies like Halborn, providing blockchain security, and Inspiren, using AI to enhance patient safety in healthcare​. Third Prime's team is composed of seasoned professionals with backgrounds in law, investment banking, and technology. Key members include Mike Kim, with over a decade of investment experience, and Jenny Bloom, a former corporate associate at Wilson Sonsini. This experienced team supports Third Prime's mission to drive success through independent thinking, focus, and rigor.

Third Rock Ventures is a venture capital firm based in Boston and San Francisco, specializing in the life sciences sector. Since its founding in 2007, Third Rock has focused on investing in transformative biotech companies with the potential to make significant impacts on patients' lives. The firm has raised over $3.4 billion across multiple funds, with its most recent fund closing at $1.1 billion in June 2022. Notable investments include bluebird bio, Editas Medicine, and Relay Therapeutics. Third Rock is known for its hands-on approach, often playing a leading role in the formation and early development of its portfolio companies. They invest heavily in early-stage projects, supporting them through significant milestones with substantial capital injections. Third Rock Ventures has built a robust portfolio with companies such as Marea Therapeutics, Seaport Therapeutics, and Synnovation Therapeutics. Their strategic focus areas include gene therapy, immuno-oncology, precision medicine, and neuropsychiatry.

Thirty Five Ventures, founded by NBA star Kevin Durant and his business partner Rich Kleiman, is an investment firm with a diverse portfolio spanning over 100 companies. The firm invests in various sectors including fintech, health and wellness, media, and artificial intelligence. Notable investments include the fitness tech company WHOOP, which recently reached a valuation of $3.6 billion, and the food delivery service Postmates, which was acquired by Uber. Thirty Five Ventures also emphasizes investments in sports and media, owning stakes in teams like Gotham FC in the National Women's Soccer League and the Major League Pickleball team, the Brooklyn Aces. The firm’s media arm, Boardroom, produces content that highlights the intersection of sports, business, and culture, and includes projects like the Emmy-nominated documentary "NYC Point Gods." Since its inception in 2016, Thirty Five Ventures has focused on creating value not just through capital, but also through strategic partnerships and leveraging its extensive network. This approach has helped the firm achieve substantial returns and maintain a dynamic presence in the venture capital landscape.

Threshold Ventures is a Menlo Park-based early-stage venture capital firm, born from the rebranding of DFJ in 2019. The firm has a clear focus on investing in innovative technology companies during critical "threshold moments" when market, technology, and societal changes create disruptive opportunities. The team, led by partners Emily Melton and Josh Stein, boasts deep experience in backing transformative startups, particularly in software, AI, healthcare, and enterprise sectors. Threshold is renowned for its conviction-led strategy, preferring to build concentrated portfolios in high-potential companies rather than spreading investments thin. They’ve backed notable startups such as Livongo, Doximity, BetterUp, Rippling, and Talkdesk, many of which have grown into industry leaders or achieved successful exits through IPOs or acquisitions. With their recent funds, Threshold IV and Threshold Select, which together raised over $450 million, the firm continues to focus on early-stage investments, primarily at the seed and Series A levels. The team remains deeply committed to helping founders grow, offering not just capital but hands-on support and mentorship. Their disciplined approach allows them to stay closely engaged with their portfolio companies, ensuring tailored guidance and strategic input during pivotal growth phases.

Thrive Capital, founded in 2009 by Joshua Kushner, is a prominent venture capital firm based in New York City. Specializing in internet, software, and technology-enabled companies, Thrive has made significant investments in high-profile startups like Instagram, GitHub, Spotify, and Twitch. They focus on early to late-stage ventures, recently closing their eighth fund at $3 billion, with $500 million dedicated to early-stage and $2.5 billion to late-stage investments. Their investment strategy emphasizes a hands-on approach, providing operational support and often taking board seats in portfolio companies. Thrive's notable exits include Affirm, Nubank, and Warby Parker, showcasing their knack for scaling successful businesses. Thrive typically writes substantial checks and is known to lead investment rounds, with an average check size varying by stage. Key team members include founder Joshua Kushner, who brings a wealth of entrepreneurial and investment expertise. Thrive prefers to build strong relationships with founders, encouraging innovative ideas and long-term growth. They are open to various approaches but value clear, compelling pitches that demonstrate potential for substantial impact and growth. For startups seeking investment, Thrive Capital is an ideal partner for those looking to leverage expertise in scaling and achieving market dominance in the tech sector​

Thursday Ventures is a venture capital firm based in Mill Valley, California, founded in 2017. The firm specializes in early-stage investments, particularly in the Pre-Seed, Seed, and Series A stages. They focus on transformative technologies in sectors such as frontier tech, deep tech, biotech, clean technologies, enterprise applications, and health tech. Thursday Ventures typically deploys between $500,000 and $1 million per investment, partnering with exceptional entrepreneurs from the inception of their companies. Their portfolio includes notable investments in companies like Whoop, Formant, and Brainchain.AI. The firm has been instrumental in the growth of these companies, providing not just capital but also strategic support and talent acquisition services. The firm has made 25 investments and has a strong track record with two unicorns in their portfolio. Their investment strategy is geared towards industries capable of significant market disruption and growth potential, aiming for outcomes of 100x to 1000x returns. The leadership team includes key figures such as Andrew Schmidt, Eric Quinn, and Ryan McKillen, who bring extensive experience from backgrounds in science, engineering, and operations at companies like Uber and Neuralink.

Tiger Global Management, founded in 2001 by Chase Coleman III, is a leading investment firm that focuses on internet, software, consumer, and financial technology companies. The firm has made significant investments in some of the most notable high-growth companies globally. Among its prominent investments are Alibaba, Facebook, LinkedIn, and Spotify. More recent investments include companies like OpenAI, Roblox, Square, and SentinelOne​​. Tiger Global's investment strategy is characterized by its aggressive approach to deal-making, often moving quickly to close deals and providing substantial funding to its portfolio companies. This strategy has helped the firm build a diverse portfolio, which includes a significant number of unicorns and high-profile public companies​. The firm has also been involved in substantial funding rounds for tech startups, such as OpenAI's $11.3 billion funding round, which has significantly impacted the AI industry. Their ability to identify and support innovative companies early has been a hallmark of their success.

Tikehau Capital is a global alternative asset manager that focuses on providing innovative investment solutions across private equity, private debt, real assets, and capital markets strategies. Founded in 2004 and headquartered in Paris, Tikehau has grown significantly, managing over €40 billion in assets. The firm has established itself as a leader in sustainable and impact investing, integrating environmental, social, and governance (ESG) factors into its investment processes. Tikehau Capital targets a wide range of sectors, including real estate, energy transition, and infrastructure, aiming to support businesses that drive long-term value creation. The firm’s entrepreneurial approach is one of its core strengths, enabling it to partner with companies at various stages of growth and provide tailored financial solutions that align with their specific needs. In addition to its investment expertise, Tikehau Capital is deeply committed to sustainability, positioning itself as a key player in the global transition to a low-carbon economy. Through its diverse range of funds, the firm invests in companies that are making a positive environmental and social impact, ensuring that financial returns are coupled with meaningful contributions to a more sustainable future. Tikehau Capital’s global reach and strong expertise across asset classes make it a trusted partner for institutional investors, entrepreneurs, and corporations seeking to navigate complex financial landscapes and achieve long-term growth.

TLV Partners, founded in 2015 and based in Tel Aviv, is an early-stage venture capital firm that focuses on backing Israeli tech startups. The firm manages over $1 billion in assets across five funds, with a strong emphasis on sectors like AI, cybersecurity, developer tools, fintech, and biotech. TLV Partners typically invests in seed and Series A rounds, with initial investments ranging between $4 million to $8 million. Founded by experienced venture capitalists Rona Segev and Eitan Bek, the firm is committed to building long-term relationships with founders, offering not only capital but also operational expertise and access to its extensive network. TLV Partners has a portfolio of companies that are shaping the future of industries, including Token Security, Next Insurance, and Rapyd. Known for its founder-first approach, TLV Partners seeks to empower visionary entrepreneurs by providing significant capital resources and deep strategic support to help build category-defining companies. The firm has raised multiple funds, with its latest, Fund V, closing at $250 million in 2023.

TMT Investments is a venture capital firm headquartered in Saint Helier, Jersey, focused on early-stage technology companies with high growth potential. Since its inception in 2010, the firm has developed a diverse portfolio across sectors such as SaaS, fintech, big data, cloud, e-commerce, and marketplaces. Some of its notable investments include Bolt, a leading European ride-hailing and delivery platform, and PandaDoc, a contract management software provider. TMT primarily targets fast-growing tech companies, often investing in startups that leverage digital innovation to disrupt traditional industries. They prefer companies that demonstrate scalable business models with global market ambitions. Their strategy is to invest early and work closely with companies through subsequent funding rounds, sometimes participating in follow-on investments as the company grows. The firm's geographic focus spans the US, UK, and Europe, with a flexible approach to opportunistic investments in emerging markets. With over 90 investments and more than 50 active portfolio companies, TMT typically writes initial checks in the range of $1-5 million, positioning itself as an active investor. Co-founded by Artyom Inyutin and Alexander Morgulchik, TMT’s leadership has a strong background in both tech and finance, helping to guide portfolio companies through growth challenges. The firm’s expertise and track record of successful exits, including high-profile companies like ShareThis and PandaDoc, make it a key player in the global tech investment scene.

Toba Capital, founded in 2012 and headquartered in Los Angeles and Newport Beach, CA, is an early-stage venture capital firm with $1.3 billion in assets under management. The firm focuses on investments in SaaS, IT infrastructure, and climate technology, aiming to support businesses capable of long-term growth and significant market impact. Toba Capital typically invests at the seed and Series A stages. Notable investments in their portfolio include companies like Alteryx, which went public, and Perimeter 81, a cybersecurity firm acquired by Check Point Software. Other significant portfolio companies are WSO2, a middleware solutions provider, and Scoutbee, a supplier discovery platform. Toba Capital has also seen successful exits with companies like Grow, acquired by Epicor, and NurseGrid, acquired by HealthStream. Toba Capital is distinguished by its commitment to philanthropy, donating 50% of its profits to charitable causes. The team, led by founders Brinkley Morse, Wilder Ramsey, and Vincent Smith, leverages extensive industry experience to support and guide their portfolio companies towards growth and success. For more detailed information on their portfolio and investment activities, you can visit Toba Capital's website or review their profiles on investment platforms like PitchBook and Crunchbase.

Torch Capital, founded in 2018 by Jonathan Keidan, is a New York-based venture capital firm renowned for investing in consumer technology companies. Their portfolio features notable startups such as Acorns, Sweetgreen, and Ro, emphasizing their focus on transformative consumer platforms and digital services. Torch Capital primarily invests in consumer-facing sectors including fintech, healthcare, and e-commerce, targeting solopreneurs and small businesses with innovative business tools. Geographically, Torch Capital concentrates its investments in the United States, with a significant presence in New York. The firm’s investment strategy centers on early-stage ventures, typically participating in seed and Series A rounds, with investment checks ranging from $1 million to $5 million. They prioritize partnering with visionary founders who can leverage technology to scale rapidly and create market leaders. The Torch Capital team comprises seasoned professionals with diverse backgrounds. Jonathan Keidan, the founder and managing partner, brings extensive experience from the intersection of media, technology, and entertainment. Other key team members include partners Sam Jones and Katie Reiner, as well as principal Chris Harper and CFO Anna Bitton.

TotalEnergies Ventures, now operating as Total Carbon Neutrality Ventures (TCNV), is the venture capital arm of TotalEnergies, focused on advancing clean and sustainable energy solutions. With an investment capacity of $400 million, the fund is dedicated to supporting startups that contribute to reducing carbon emissions and fostering a low-carbon future. Their areas of interest include renewable energy, energy storage, smart mobility, bioplastics, and circular economy initiatives. TCNV aims to drive TotalEnergies' mission to become a responsible energy leader by investing in innovative technologies that help reduce the carbon footprint of industries globally. The fund operates with teams based in Europe and the United States, backing startups from early to late stages, with typical investments ranging between €100,000 and €1.5 million. Some notable portfolio companies include Solidia, Ionic Materials, and AutoGrid, all contributing to carbon-neutral technologies. Through its ventures, TotalEnergies not only provides capital but also leverages its vast industry expertise and global network to help startups scale and succeed in the energy transition. This aligns with the company’s broader goal of achieving net-zero emissions by 2050.

Toyota Ventures, based in the San Francisco Bay Area, is the early-stage venture capital arm of Toyota, focusing on frontier technologies like AI, robotics, smart cities, and climate tech. They have a global investment scope, backing startups from all over the world. Notable investments include Joby Aviation, developing eVTOL aircraft; Drishti, enhancing factory operations with AI; and e-Zinc, innovating long-duration energy storage. Their strategy emphasizes early-stage investments, often leading rounds with an average check size tailored to the needs of each startup. Toyota Ventures actively supports their portfolio companies with strategic guidance and extensive industry connections. They prioritize startups with scalable solutions and strong potential for market disruption. Key team members include Jim Adler, founder and general partner, who brings a rich background in data privacy and big data analytics, and Natalie Fonseca Licciardi, managing partner, known for her expertise in tech policy and governance. The team is committed to fostering innovation and guiding startups through the complexities of growth and market entry. For startups looking to engage, Toyota Ventures values clear, compelling pitches that demonstrate technological innovation and market potential. They build their investment funnel through proactive scouting and a robust network, ensuring a diverse and dynamic portfolio​.

The Rise Fund, established by TPG in partnership with Bono and Jeff Skoll in 2016, is a global impact investing firm with a commitment to achieving social and environmental impact alongside competitive financial returns. The fund focuses on sectors that address the United Nations' Sustainable Development Goals (UN SDGs), including education, energy, food and agriculture, financial services, healthcare, and technology. Notable investments by The Rise Fund include companies like C3.ai, a leading enterprise AI software provider; Form Energy, which is developing low-cost, long-duration energy storage solutions; and Benevity, a global leader in corporate purpose software. Other significant investments include Fourth Partner Energy, a provider of distributed solar energy solutions, and EverFi, an education technology company. The fund has successfully managed over $18 billion in assets, encompassing The Rise Funds, TPG Rise Climate, and the Evercare Health Fund. The Rise Fund has been instrumental in driving positive change, with notable exits such as C3 AI and DreamBox Learning, and impactful investments in companies like Enpal, a solar energy provider, and LiveKindly, a collective promoting plant-based food solutions. The Rise Fund is known for its rigorous impact measurement and management practices, ensuring that their investments deliver tangible social and environmental benefits. The team at The Rise Fund leverages their extensive network and resources to support the growth and success of their portfolio companies.

TQ Ventures is a venture capital firm based in New York City, founded in 2018 by Andrew Marks, Schuster Tanger, and Scooter Braun. The firm focuses on partnering with exceptional founders at the earliest stages, investing primarily in seed and Series A rounds. TQ Ventures has a diverse portfolio across various sectors, including consumer tech, fintech, healthcare, software, and gaming. The firm has backed over 40 companies in the United States, Europe, and Asia. Notable investments include Clubhouse, Kindbody, Liquid IV, and Noom. TQ Ventures aims to support innovative companies that have the potential to transform their respective industries. Andrew Marks, one of the co-founders, has extensive experience in investment, having previously worked at Freemark Partners and Blue Ridge Capital. His leadership, along with the expertise of his co-founders, positions TQ Ventures as a significant player in the venture capital landscape.

TRAC VC is an innovative venture capital firm based in San Francisco, known for its data-driven approach to identifying and investing in early-stage startups. The firm leverages collective intelligence, data analysis, and mathematical models to pinpoint future unicorns, generally participating in the 2nd or 3rd funding rounds of promising startups. TRAC VC's diverse portfolio includes notable investments such as GreenPark Sports, which enhances the experience of sports and esports fans; Laskie, a platform that matches job opportunities with remote candidates; and Yumi, a provider of freshly made organic baby food. Other significant investments include Redbird, a no-code data analytics platform, and Outer, a company specializing in innovative outdoor furniture​. Founded in 2019 by Fredrick Campbell and Joseph Aaron, TRAC VC has made a total of 95 investments, with a recent focus on industries such as healthcare technology, business productivity software, and multimedia design software. They are particularly known for their ability to move quickly and make significant impacts through strategic support and introductions within their extensive network​. The firm's investment strategy is characterized by a focus on scalable growth and market disruption, with an average investment round size of $4 million. TRAC VC's approach emphasizes the importance of data and collective intelligence in making informed investment decisions, ensuring that their portfolio companies have strong foundations and high potential for success​.

Trailhead Capital is a mission-driven venture capital firm based in Boulder, Colorado, focused on creating financial, societal, and ecological returns by investing in regenerative food and agriculture. Founded by Bobby Pelz and Tripp Wall, Trailhead Capital backs early-stage companies that are driving innovations across the food value chain, from farm to supply chain to consumer. The firm targets Seed and Series A investments in tech-enabled solutions that promote regenerative practices, aiming to transform food systems and foster sustainability. With its inaugural $50 million Regeneration Fund I, Trailhead Capital has supported 22 companies to date, with two successful exits. The firm’s portfolio includes groundbreaking companies such as EarthSense, which develops autonomous robots for agricultural research, and Ascribe Bioscience, a biotech startup focusing on natural crop protection. The firm is a Certified B Corp, underscoring its commitment to positive environmental and social impact. Trailhead Capital’s approach emphasizes the intersection of technology and regenerative agriculture, leveraging advancements to improve soil health, reduce carbon emissions, minimize food waste, and enhance the quality of food.

Trajectory Ventures is a venture capital firm in NYC that advances disruptive tech-savvy ventures across various funding stages.

Triatomic Capital is an early-stage venture capital firm focusing on "century-defining" technologies. The firm invests in deep tech sectors like engineered biology (including cell and gene therapies, synthetic biology, and AI-driven drug discovery), energy innovations (battery tech, nuclear fusion), and advanced computing (AI processors, quantum computing). Their mission is to support startups that push the boundaries in areas critical to future industries, including digital infrastructure, automation, and nanomaterials. Triatomic operates from offices in New York, San Francisco, and Hong Kong, giving it a broad geographical reach. The firm typically participates in Seed to Series A rounds, with check sizes ranging from $250K to $25M, though they don’t always lead investment rounds. Recent high-profile investments include Chemify, which leverages AI to digitize chemical discovery, and Betteromics, a bioinformatics platform for life sciences. The leadership team, co-founded by Jeff Huber, former Google executive and founding CEO of GRAIL, brings extensive experience in scaling tech and biotech companies. Huber’s background in applying AI and leading life-saving innovations plays a pivotal role in guiding Triatomic's investment strategy.

Tribe Capital, established in 2018, is a venture capital firm based in San Francisco, California. The firm manages over $1.6 billion in assets, focusing on investments from seed to growth stages across various sectors, including technology and cryptocurrency. Tribe Capital employs a data-driven approach to identify and amplify early-stage product-market fit, aiming to invest in companies with the potential to become category leaders. Founded by Arjun Sethi, Jonathan Hsu, and Ted Maidenberg, Tribe Capital leverages the extensive experience of its founders, who have previously built and invested in notable companies like Facebook, Gusto, and Slack. The firm emphasizes a bottom-up investment strategy, aiming to be the best capital allocators by iterating rapidly and maintaining a strong focus on product-market fit. Tribe Capital's portfolio includes companies such as Carta, Relativity Space, Shiprocket, Kraken, and Bolt. The firm also has a strong presence in the cryptocurrency market, investing in projects like Berachain, Akash, and Cyberconnect.

TriplePoint Capital is a leading venture capital firm specializing in providing financing solutions to high-growth, venture capital-backed companies. Established in Menlo Park, TriplePoint offers a range of financial products including debt financing, equity capital, and leases. They target companies in sectors such as technology, life sciences, and other high-growth industries. TriplePoint Capital manages over $9 billion in assets and has financed more than 3,000 companies globally. Their portfolio includes notable investments like Facebook, YouTube, and Airbnb. The firm’s investment strategy focuses on providing flexible, customized financial solutions tailored to the unique needs of each company, from seed stage to pre-IPO. The leadership team includes co-founders Jim Labe and Sajal Srivastava, who bring extensive experience in venture finance and have played key roles in establishing venture lending as a crucial source of capital for startups.

Triventures is a global, early-stage venture capital firm founded in 2010, with offices in Israel and Silicon Valley. The firm invests in innovative companies that converge technology and healthcare to solve critical industry challenges. Triventures manages $200 million in assets and reviews over 700 companies annually, focusing on sectors such as data-driven healthcare, tech-health convergence, and disruptive medical devices​. The Triventures team, led by co-founders Michal Geva and Dr. Peter Fitzgerald, has extensive experience in entrepreneurship and investment, having guided over 30 companies to successful exits. They emphasize partnerships with entrepreneurs to build value-creating companies that reshape healthcare through data-driven solutions and access to significant health data assets, particularly through their collaboration with Sheba Medical Center​. Notable investments include companies like Ginkgo Bioworks, Atomwise, and Verge Genomics, highlighting their focus on pioneering breakthroughs in genomics, synthetic biology, and advanced diagnostics.

Trousdale Ventures is a venture capital firm founded in 2018 by Phillip Sarofim and is based in West Hollywood, California. The firm focuses on investing in transformative companies across several sectors, including space and mobility, climate tech, consumer goods, and deep tech. Trousdale Ventures looks for companies with the potential to disrupt industries and create long-term societal impact, aiming to build "forever companies" that leave a lasting legacy. The firm's investment strategy is centered on supporting visionary entrepreneurs who tackle large-scale challenges and redefine industries. Some notable portfolio companies include Solugen, which is revolutionizing sustainable chemistry, and CesiumAstro, a leader in satellite technology. Trousdale Ventures also emphasizes collaboration with its portfolio companies, providing more than just financial backing by offering strategic guidance to scale their innovations. Trousdale is particularly active in sectors driving societal progress, such as space exploration, sustainable technologies, and health and wellness. The firm's mission is to shape the future by investing in companies that align with its vision of improving quality of life and driving innovation that transcends generations.

True Ventures is a distinguished venture capital firm that has been a significant player in early-stage investments since its inception in 2005. The firm has invested $3.8 billion across over 350 startups, fostering innovation in sectors such as personal wellness, robotics, therapeutics, climate technologies, and ocean exploration. Notable investments from True Ventures include companies like Peloton, Fitbit, Blue Bottle Coffee, Ring, and Sweetgreen. These investments showcase their ability to identify and support high-growth startups across various industries. The firm typically invests in the seed and Series A stages, providing initial funding and reserving capital for follow-on investments. Geographically, True Ventures focuses primarily on the United States, with headquarters in Palo Alto and additional offices in San Francisco. Their investment strategy emphasizes partnering with visionary founders who are tackling significant problems and bringing innovative solutions to market. True Ventures aims to take a collaborative approach, working closely with entrepreneurs to guide their growth and development. The firm is led by a seasoned team of partners including Jon Callaghan, Tony Conrad, and Om Malik, who bring deep expertise and a strong track record in venture capital. Founders looking to connect with True Ventures should demonstrate a clear vision and a compelling value proposition that aligns with the firm’s focus on transformative technologies and impactful solutions. True Ventures is renowned for its active involvement in the startup ecosystem, often leading investment rounds and providing substantial strategic support to its portfolio companies, helping them navigate the complexities of scaling their businesses.

True Wealth Ventures is an Austin-based venture capital firm, co-founded by Sara Brand and Kerry Rupp in 2015. The firm focuses exclusively on early-stage investments in women-led startups, particularly those aiming to improve environmental and human health. Their portfolio includes companies like BrainCheck and Flourish, showcasing their commitment to healthcare and sustainable innovations. True Wealth Ventures is driven by the belief that women-led companies outperform and deserve greater support, especially given that women control a growing portion of U.S. assets yet remain underrepresented in venture capital. Their investments target companies with strong female leadership, requiring that at least one woman in a key decision-making role is involved. The firm has raised over $60 million across two funds, with a typical check size between $200,000 and $500,000. True Wealth Ventures stands out for its active involvement, offering deep operational support through its extensive network of female investors and advisors, creating a "virtuous circle" of impact investment.

Trust Ventures is a venture capital firm based in Austin, Texas, that focuses on investing in startups tackling significant societal challenges in highly regulated industries. Founded in 2018, the firm has raised multiple funds, with its third and largest fund closing at $200 million. Trust Ventures primarily targets sectors such as clean energy, affordable housing, and quality healthcare, aiming to help startups navigate and overcome policy barriers that hinder innovation. The firm’s investment strategy is distinctive; it provides not just capital but also strategic guidance to help startups address regulatory challenges. This hands-on approach includes building relationships, developing strategies, and advocating for policy changes to level the playing field against larger, incumbent companies. Trust Ventures looks for startups with disruptive technologies that have the potential to solve pressing societal problems but are often stymied by outdated policies. Key team members include co-founders Salen Churi, who has a background in law and academia, and Brian Tochman, a seasoned entrepreneur and former private equity executive. Together, they leverage their expertise to support portfolio companies in achieving growth and navigating complex regulatory landscapes. Notable investments from Trust Ventures include companies like Sana Benefits, ICON, and Oklo, all of which are pioneering in their respective fields. The firm is dedicated to being an active partner, ensuring that their portfolio companies can reach their full potential and bring meaningful solutions to market.

TSI Investment Ltd., based in Dubai, is a diversified investment group specializing in providing financial, operational, and managerial support to its subsidiaries across a wide range of industries, including construction, real estate, energy, and F&B. TSI focuses on identifying and nurturing investment opportunities, helping companies grow into industry leaders by leveraging synergies between its portfolio businesses. The company's foundation lies in its successful ventures in Engineering, Procurement, and Construction (EPC) services, especially in cooling, energy systems, and IT security. Over time, TSI has expanded its portfolio to include trading and strategic partnerships, continuously seeking new opportunities to strengthen its holdings. One of TSI’s standout projects is its involvement with Cylingas, a fabrication company specializing in oil and gas storage solutions, further demonstrating its extensive expertise in industrial sectors. Additionally, TSI is engaged in international ventures, investing in cutting-edge sectors such as IT infrastructure and sustainable energy​. With a strategic focus on growth and scalability, TSI remains committed to its vision of developing companies that not only meet but exceed stakeholder expectations.

TSVC, formerly known as TEEC Angel Fund, is a venture capital firm that specializes in deep technology investments. Founded in 2012, TSVC focuses on early-stage startups that leverage breakthroughs in science and engineering. The firm is based in Silicon Valley and has a strong track record of identifying and nurturing innovative companies. TSVC's portfolio includes notable investments in companies such as Quanergy Systems, a leading provider of LiDAR sensors and smart sensing solutions; Jasper Therapeutics, which develops novel therapies for hematologic disorders; and Valant, a behavioral health software company. The firm has been instrumental in helping these companies scale and achieve significant market success​​. The firm's investment strategy is centered on high-impact verticals, including enterprise SaaS, fintech, techbio, consumer tech, and crypto. TSVC aims to support founders with strategic counsel and hands-on expertise in areas like software engineering, data science, and quantitative modeling. This approach has enabled TSVC to build a diverse and robust portfolio of companies that are fundamentally transforming traditional industries​​. With over 100 companies in its portfolio, TSVC continues to drive innovation and support the next generation of entrepreneurs. The firm’s commitment to leveraging data science and computing advances positions it as a key player in the venture capital landscape, dedicated to fostering groundbreaking technologies and solutions​.

Tuesday Capital, formerly known as CrunchFund, is a dynamic venture capital firm that backs early-stage startups. Notable investments include GitLab, Kueski, AirTable, Human Interest, and DigitalOcean. With a focus on technology, health tech, and high-growth sectors, Tuesday Capital maintains a sector-agnostic approach, giving them a broad investment landscape. Geographically, they are based in Austin and San Francisco but invest globally, supporting founders wherever they are. Their strategy revolves around a hands-on approach, actively helping startups with everything from strategic guidance to PR and marketing. Typically investing in seed rounds, Tuesday Capital writes checks averaging $5M and often co-invests with other VCs. They prefer to be approached through their extensive network or via a compelling pitch that clearly aligns with their vision. Co-founders Patrick Gallagher and Michael Arrington lead the team with significant expertise and a proven track record. Gallagher, based in Austin, brings over two decades of venture experience, previously working with VantagePoint and Morgan Stanley. Arrington, located in Broomfield, adds media and tech industry insights to the firm’s operations. Tuesday Capital’s portfolio boasts several unicorns, including Human Interest, Forward, and Zipline. Their active involvement in the startup ecosystem and commitment to founder success make them a notable partner in the venture capital landscape

Twin Path Ventures is a dynamic venture capital firm based in London, specializing in early-stage investments across deep-tech and AI-driven sectors. Founded in 2023, the firm focuses on backing visionary startups that are poised to disrupt industries such as healthcare, fintech, and enterprise software. Twin Path typically invests in pre-seed and seed-stage companies, with an average ticket size of £500,000. They lead most of the rounds they participate in but also co-invest alongside other strategically aligned VCs. Their fund structure is designed to optimize tax efficiency, blending SEIS, EIS, and non-tax funds, which allows them to offer investors tax-free capital growth through a diverse portfolio of tech-driven businesses. Notable investments include Causa Tech, a leader in AI-driven productivity software, and FinCrime Dynamics, which focuses on advanced fraud detection and prevention software. Twin Path operates with a hands-on approach, providing strategic guidance and operational expertise to help portfolio companies navigate growth challenges. The team is led by General Partner John Spindler, a seasoned investor with deep roots in the UK venture ecosystem, including his previous role as CEO of Capital Enterprise and co-founder of the London Co-Investment Fund. Katie Lockwood and Nick Slater, both partners, bring complementary expertise in bioscience, intellectual property, and deep-tech startups, creating a robust support network for the companies they back. Twin Path Ventures is gaining recognition in the UK, recently being named a finalist for the 2023 Seed VC of the Year at the UKBAA Angel Investment Awards.

Two Sigma Ventures, established in 2012 and based in New York, is a venture capital firm specializing in early-stage investments. The firm focuses on sectors such as artificial intelligence, data science, healthcare, biotechnology, and fintech. Notable investments include companies like Recursion Pharmaceuticals, GitLab, and Ripple. They have a portfolio of 113 companies and have achieved 25 successful exits. Two Sigma Ventures typically invests between $500,000 to $5 million, leveraging its expertise in data and technology from its parent company, Two Sigma Investments, to support innovative startups​.

U.S. Venture Partners (USVP) is a leading Silicon Valley venture capital firm with a long history of investing in early-stage companies across four primary sectors: cybersecurity, enterprise software, consumer, and healthcare. Founded in 1981, USVP has invested in over 500 companies, helping to launch industry leaders like Box, Yammer, Pluto TV, Inari Medical, and Check Point Software. With a total of 93 IPOs and more than 100 profitable acquisitions, the firm has built a strong reputation for identifying transformative startups. USVP typically leads Series A and B rounds, focusing on high-growth opportunities in the U.S. and Israel. The firm’s team consists of former entrepreneurs and experienced executives who offer strategic support in scaling, team building, product development, and business growth. Its most recent fund, USVP XIII, closed at $400 million, continuing its legacy of early-stage investments aimed at transforming global industries.

The UCL Technology Fund (UCLTF) is a venture capital fund established in 2016 to commercialize cutting-edge research originating from University College London (UCL). Managed in partnership with AlbionVC and UCL Business, the fund focuses on investing in intellectual property arising from UCL's research in life sciences, physical sciences, and engineering. UCLTF plays a pivotal role in taking groundbreaking technologies from early-stage proof of concept through to commercialization, either via licensing or by forming spinout companies. With an emphasis on life sciences, the fund supports pioneering projects in areas such as gene therapy, oncology, and advanced materials. Notable investments include Orchard Therapeutics, a spinout specializing in rare disease gene therapies, and Bloomsbury AI, which developed natural language processing technology before being acquired by Facebook in 2018. The fund's portfolio is diverse, encompassing companies tackling global challenges like clean energy through firms such as Carbon Re, which is focused on decarbonizing heavy industries​. The fund’s mission is not only to support UCL's world-class academic research but also to deliver societal impact and substantial commercial returns. The first fund has seen impressive successes, including two Nasdaq IPOs and raising over £1 billion in external funding across its portfolio. Recently, UCLTF closed its second fund at £100 million, further strengthening its ability to back high-impact innovations in biotech, healthcare, and AI.

Ugly Duckling Ventures is a venture capital firm based in Copenhagen, Denmark, founded in 2021. It focuses on early-stage investments, particularly at the pre-seed and seed stages, within the Nordic region. The firm is led by a team of experienced founders and business angels who prioritize building strong relationships with the startups they back, offering not only capital but also operational expertise to help early ventures scale quickly. The firm targets disruptive business models and industries with growth potential across various sectors, including software, e-commerce, and sustainability. Ugly Duckling Ventures is known for its hands-on, collaborative approach, providing startups with direct access to general partners rather than delegating them to junior managers. The firm is actively involved in the Danish startup ecosystem, with many of its investors contributing to the success of portfolio companies like Moxso, BeCause, and Juristic. In 2023, Ugly Duckling closed a DKK 150 million (approximately $22 million) fund to support Danish startups, typically investing around $1.6 million per round. Their focus on transparency and founder-first partnerships makes them a valuable ally for early-stage companies.