AI & Deep Tech VC Funds

Tribeca Venture Partners (TVP), established in 2011 and headquartered in New York City, is an early-stage venture capital firm that focuses on investing in emerging technologies and disruptive business models. The firm primarily invests in sectors such as SaaS, marketplaces, fintech, and martech, emphasizing companies that have the potential to create or transform large markets. TVP's portfolio includes notable investments like ACV Auctions, an online wholesale automotive auction platform that went public, and AlphaSense, an AI-driven market intelligence platform valued at $2.5 billion. Other significant investments include RealBlocks, a blockchain-based platform for real estate transactions, and Honey, a browser extension that finds discount codes for online shoppers, which was acquired by PayPal​. The firm typically leads Series A rounds with initial investments ranging from $1 to $6 million and follows on through Series B. TVP's investment approach is heavily focused on the New York tech ecosystem, leveraging their extensive local network and deep industry expertise to support portfolio companies. They pride themselves on being deeply involved and committed partners, providing not just capital but also strategic guidance and operational support to help founders navigate challenges and scale their businesses effectively.

TriplePoint Capital is a leading venture capital firm specializing in providing financing solutions to high-growth, venture capital-backed companies. Established in Menlo Park, TriplePoint offers a range of financial products including debt financing, equity capital, and leases. They target companies in sectors such as technology, life sciences, and other high-growth industries. TriplePoint Capital manages over $9 billion in assets and has financed more than 3,000 companies globally. Their portfolio includes notable investments like Facebook, YouTube, and Airbnb. The firm’s investment strategy focuses on providing flexible, customized financial solutions tailored to the unique needs of each company, from seed stage to pre-IPO. The leadership team includes co-founders Jim Labe and Sajal Srivastava, who bring extensive experience in venture finance and have played key roles in establishing venture lending as a crucial source of capital for startups.

Triventures is a global, early-stage venture capital firm founded in 2010, with offices in Israel and Silicon Valley. The firm invests in innovative companies that converge technology and healthcare to solve critical industry challenges. Triventures manages $200 million in assets and reviews over 700 companies annually, focusing on sectors such as data-driven healthcare, tech-health convergence, and disruptive medical devices​. The Triventures team, led by co-founders Michal Geva and Dr. Peter Fitzgerald, has extensive experience in entrepreneurship and investment, having guided over 30 companies to successful exits. They emphasize partnerships with entrepreneurs to build value-creating companies that reshape healthcare through data-driven solutions and access to significant health data assets, particularly through their collaboration with Sheba Medical Center​. Notable investments include companies like Ginkgo Bioworks, Atomwise, and Verge Genomics, highlighting their focus on pioneering breakthroughs in genomics, synthetic biology, and advanced diagnostics.

Trucks VC is a venture capital firm based in San Francisco, specializing in early-stage investments in the future of transportation. The firm focuses on supporting companies that are innovating to make transportation more decarbonized, safer, and more accessible. Key sectors include autonomous vehicles, electric vehicles, and transportation software. Notable investments from Trucks VC include Joby Aviation, an air taxi service; Bear Flag Robotics, which was acquired by John Deere; and Roadster, an e-commerce platform for vehicle dealerships acquired by CDK Global. The firm also invested in nuTonomy, an autonomous vehicle software company acquired by Delphi, and Zendrive, a driver safety analytics company acquired by Intuit. The firm was co-founded by Reilly Brennan, Jeffrey Schox, and Kathryn Schox, who bring extensive experience in the automotive and venture capital industries. The team is dedicated to identifying and supporting startups that align with their mission to transform transportation. Trucks VC recently launched their Trucks Growth Fund to invest in later-stage rounds of their portfolio companies, continuing their commitment to fostering innovation in the transportation sector​.

True Incube is Thailand’s leading startup incubator and accelerator, backed by True Corporation and CP Group. Launched in 2013, True Incube focuses on investing in early-stage startups across Southeast Asia, with a strong emphasis on technologies that enhance True's core competencies in telecom and related industries. Its investment sectors include smart industries, AI, automation, fintech, health tech, and digital B2B/B2C solutions. The incubator supports startups through direct investments, strategic partnerships, and mentorship, helping them scale regionally. True Incube also offers a robust accelerator program that provides resources such as networking, funding, and access to True's ecosystem of technology and infrastructure. Notable investments include QueQ, Credit OK, and Peak, among others. These investments aim to integrate innovative technologies into Thailand's digital ecosystem and beyond. With a focus on scalable, capital-efficient businesses, True Incube is a key player in Southeast Asia’s tech and startup scene, driving innovation in industries such as IoT, digital healthcare, and smart cities.

True Ventures is a distinguished venture capital firm that has been a significant player in early-stage investments since its inception in 2005. The firm has invested $3.8 billion across over 350 startups, fostering innovation in sectors such as personal wellness, robotics, therapeutics, climate technologies, and ocean exploration. Notable investments from True Ventures include companies like Peloton, Fitbit, Blue Bottle Coffee, Ring, and Sweetgreen. These investments showcase their ability to identify and support high-growth startups across various industries. The firm typically invests in the seed and Series A stages, providing initial funding and reserving capital for follow-on investments. Geographically, True Ventures focuses primarily on the United States, with headquarters in Palo Alto and additional offices in San Francisco. Their investment strategy emphasizes partnering with visionary founders who are tackling significant problems and bringing innovative solutions to market. True Ventures aims to take a collaborative approach, working closely with entrepreneurs to guide their growth and development. The firm is led by a seasoned team of partners including Jon Callaghan, Tony Conrad, and Om Malik, who bring deep expertise and a strong track record in venture capital. Founders looking to connect with True Ventures should demonstrate a clear vision and a compelling value proposition that aligns with the firm’s focus on transformative technologies and impactful solutions. True Ventures is renowned for its active involvement in the startup ecosystem, often leading investment rounds and providing substantial strategic support to its portfolio companies, helping them navigate the complexities of scaling their businesses.

True Wealth Ventures is an Austin-based venture capital firm, co-founded by Sara Brand and Kerry Rupp in 2015. The firm focuses exclusively on early-stage investments in women-led startups, particularly those aiming to improve environmental and human health. Their portfolio includes companies like BrainCheck and Flourish, showcasing their commitment to healthcare and sustainable innovations. True Wealth Ventures is driven by the belief that women-led companies outperform and deserve greater support, especially given that women control a growing portion of U.S. assets yet remain underrepresented in venture capital. Their investments target companies with strong female leadership, requiring that at least one woman in a key decision-making role is involved. The firm has raised over $60 million across two funds, with a typical check size between $200,000 and $500,000. True Wealth Ventures stands out for its active involvement, offering deep operational support through its extensive network of female investors and advisors, creating a "virtuous circle" of impact investment.

Trust Ventures is a venture capital firm based in Austin, Texas, that focuses on investing in startups tackling significant societal challenges in highly regulated industries. Founded in 2018, the firm has raised multiple funds, with its third and largest fund closing at $200 million. Trust Ventures primarily targets sectors such as clean energy, affordable housing, and quality healthcare, aiming to help startups navigate and overcome policy barriers that hinder innovation. The firm’s investment strategy is distinctive; it provides not just capital but also strategic guidance to help startups address regulatory challenges. This hands-on approach includes building relationships, developing strategies, and advocating for policy changes to level the playing field against larger, incumbent companies. Trust Ventures looks for startups with disruptive technologies that have the potential to solve pressing societal problems but are often stymied by outdated policies. Key team members include co-founders Salen Churi, who has a background in law and academia, and Brian Tochman, a seasoned entrepreneur and former private equity executive. Together, they leverage their expertise to support portfolio companies in achieving growth and navigating complex regulatory landscapes. Notable investments from Trust Ventures include companies like Sana Benefits, ICON, and Oklo, all of which are pioneering in their respective fields. The firm is dedicated to being an active partner, ensuring that their portfolio companies can reach their full potential and bring meaningful solutions to market.

TSI Investment Ltd., based in Dubai, is a diversified investment group specializing in providing financial, operational, and managerial support to its subsidiaries across a wide range of industries, including construction, real estate, energy, and F&B. TSI focuses on identifying and nurturing investment opportunities, helping companies grow into industry leaders by leveraging synergies between its portfolio businesses. The company's foundation lies in its successful ventures in Engineering, Procurement, and Construction (EPC) services, especially in cooling, energy systems, and IT security. Over time, TSI has expanded its portfolio to include trading and strategic partnerships, continuously seeking new opportunities to strengthen its holdings. One of TSI’s standout projects is its involvement with Cylingas, a fabrication company specializing in oil and gas storage solutions, further demonstrating its extensive expertise in industrial sectors. Additionally, TSI is engaged in international ventures, investing in cutting-edge sectors such as IT infrastructure and sustainable energy​. With a strategic focus on growth and scalability, TSI remains committed to its vision of developing companies that not only meet but exceed stakeholder expectations.

TSVC, formerly known as TEEC Angel Fund, is a venture capital firm that specializes in deep technology investments. Founded in 2012, TSVC focuses on early-stage startups that leverage breakthroughs in science and engineering. The firm is based in Silicon Valley and has a strong track record of identifying and nurturing innovative companies. TSVC's portfolio includes notable investments in companies such as Quanergy Systems, a leading provider of LiDAR sensors and smart sensing solutions; Jasper Therapeutics, which develops novel therapies for hematologic disorders; and Valant, a behavioral health software company. The firm has been instrumental in helping these companies scale and achieve significant market success​​. The firm's investment strategy is centered on high-impact verticals, including enterprise SaaS, fintech, techbio, consumer tech, and crypto. TSVC aims to support founders with strategic counsel and hands-on expertise in areas like software engineering, data science, and quantitative modeling. This approach has enabled TSVC to build a diverse and robust portfolio of companies that are fundamentally transforming traditional industries​​. With over 100 companies in its portfolio, TSVC continues to drive innovation and support the next generation of entrepreneurs. The firm’s commitment to leveraging data science and computing advances positions it as a key player in the venture capital landscape, dedicated to fostering groundbreaking technologies and solutions​.

TT Capital Partners is a healthcare-focused private equity firm based in Bloomington, Minnesota. Founded in 2011, TTCP invests in innovative healthcare technology and services companies with the potential to become market leaders. Their investment strategy spans various healthcare sectors, including healthcare IT, technology-enabled services, and clinical services. Notable investments in TTCP’s portfolio include Cantata Health Solutions, CareConnectMD, and DarioHealth. Cantata Health Solutions provides integrated EHR, RCM, and clinical technology solutions for behavioral health and acute care providers. CareConnectMD focuses on primary care and care coordination for high-needs Medicare populations. DarioHealth offers a digital therapeutics platform for managing chronic conditions. TTCP has a team of over 20 professionals with extensive experience in healthcare investing and operations. This expertise allows them to provide strategic insights and support to their portfolio companies, driving growth and innovation in the healthcare industry. Recent strategic moves include investments in Pyx Health, addressing loneliness and social isolation, and the merger of Revel and NovuHealth to form Icario, a health action platform.

Tuesday Capital, formerly known as CrunchFund, is a dynamic venture capital firm that backs early-stage startups. Notable investments include GitLab, Kueski, AirTable, Human Interest, and DigitalOcean. With a focus on technology, health tech, and high-growth sectors, Tuesday Capital maintains a sector-agnostic approach, giving them a broad investment landscape. Geographically, they are based in Austin and San Francisco but invest globally, supporting founders wherever they are. Their strategy revolves around a hands-on approach, actively helping startups with everything from strategic guidance to PR and marketing. Typically investing in seed rounds, Tuesday Capital writes checks averaging $5M and often co-invests with other VCs. They prefer to be approached through their extensive network or via a compelling pitch that clearly aligns with their vision. Co-founders Patrick Gallagher and Michael Arrington lead the team with significant expertise and a proven track record. Gallagher, based in Austin, brings over two decades of venture experience, previously working with VantagePoint and Morgan Stanley. Arrington, located in Broomfield, adds media and tech industry insights to the firm’s operations. Tuesday Capital’s portfolio boasts several unicorns, including Human Interest, Forward, and Zipline. Their active involvement in the startup ecosystem and commitment to founder success make them a notable partner in the venture capital landscape

Tusk Venture Partners is a New York-based venture capital firm that focuses on early-stage startups navigating highly regulated markets. Founded in 2015 by Bradley Tusk and Jordan Nof, the firm brings a unique edge with its deep expertise in political strategy and regulatory risk, allowing them to guide companies through complex legal landscapes. Their portfolio boasts high-profile investments in companies like Bird, Alto Pharmacy, Ro, and Calm, covering sectors such as digital health, fintech, transportation, and enterprise software. Tusk primarily targets startups at the pre-seed, seed, and Series A stages, often writing checks between $750K and $2M. They are well-known for backing disruptive companies that face regulatory hurdles, such as those in healthcare, insurance, and mobility. Recent exits include Lemonade, Coinbase, and FanDuel, reflecting the firm's strength in taking companies from early-stage to successful outcomes. Tusk's leadership leverages their political consulting background to give founders not just capital but also access to regulatory strategy, making them a sought-after partner for companies in complex industries. Entrepreneurs should approach Tusk with a clear understanding of their regulatory challenges and a focus on markets requiring specialized expertise.

Twenty Two VC, founded by Katherine Caldwell, is an early-stage venture capital firm based in San Francisco, California. The firm specializes in investing in ambitious founders who are building innovative companies in sectors such as SaaS, fintech, open source, marketplaces, and developer tools. Twenty Two VC stands out by investing earlier than most other investors, often engaging with companies before they have publicly launched. The portfolio of Twenty Two VC includes notable companies like Airbyte, an open-source ELT platform, BuildBuddy, which provides enterprise features for the Bazel build system, and Whatnot, the largest livestream shopping platform in the U.S. Other significant investments include Cron, a next-generation calendar for professionals, and PostHog, an open-source product operating system platform​. The firm has made over 85 investments since its founding in 2017 and is known for its quick decision-making and efficient execution, which is highly valued by founders looking to focus on their work without lengthy fundraising processes. Twenty Two VC seeks out magnetic, tenacious, and adaptable founders who are not afraid of big ideas and are committed to shipping great products.

Twin Path Ventures is a dynamic venture capital firm based in London, specializing in early-stage investments across deep-tech and AI-driven sectors. Founded in 2023, the firm focuses on backing visionary startups that are poised to disrupt industries such as healthcare, fintech, and enterprise software. Twin Path typically invests in pre-seed and seed-stage companies, with an average ticket size of £500,000. They lead most of the rounds they participate in but also co-invest alongside other strategically aligned VCs. Their fund structure is designed to optimize tax efficiency, blending SEIS, EIS, and non-tax funds, which allows them to offer investors tax-free capital growth through a diverse portfolio of tech-driven businesses. Notable investments include Causa Tech, a leader in AI-driven productivity software, and FinCrime Dynamics, which focuses on advanced fraud detection and prevention software. Twin Path operates with a hands-on approach, providing strategic guidance and operational expertise to help portfolio companies navigate growth challenges. The team is led by General Partner John Spindler, a seasoned investor with deep roots in the UK venture ecosystem, including his previous role as CEO of Capital Enterprise and co-founder of the London Co-Investment Fund. Katie Lockwood and Nick Slater, both partners, bring complementary expertise in bioscience, intellectual property, and deep-tech startups, creating a robust support network for the companies they back. Twin Path Ventures is gaining recognition in the UK, recently being named a finalist for the 2023 Seed VC of the Year at the UKBAA Angel Investment Awards.

Twine Ventures is a venture capital firm based in San Francisco, founded in 2021 by Leshika Samarasinghe. The firm focuses on early-stage investments in sectors like healthcare, climate tech, and financial empowerment, aiming to support mission-driven founders whose work ties purpose and profit. Twine invests primarily at the seed and Series A stages, offering check sizes ranging from $100,000 to $1 million. Their portfolio includes companies like Waltz Health, Rupa Health, and Alpha Grid, with a focus on leveraging technology such as AI and data science to drive improvements in healthcare and sustainability. Additionally, Twine is committed to diversity, with a strong emphasis on investing in ventures led by women and BIPOC founders. Twine operates with a hands-on approach, providing more than just capital by supporting founders with go-to-market strategies and scaling their companies through competitive fundraising.

Two Sigma Ventures, established in 2012 and based in New York, is a venture capital firm specializing in early-stage investments. The firm focuses on sectors such as artificial intelligence, data science, healthcare, biotechnology, and fintech. Notable investments include companies like Recursion Pharmaceuticals, GitLab, and Ripple. They have a portfolio of 113 companies and have achieved 25 successful exits. Two Sigma Ventures typically invests between $500,000 to $5 million, leveraging its expertise in data and technology from its parent company, Two Sigma Investments, to support innovative startups​.

Type One Ventures is a venture capital firm founded in 2019 and based in Malibu, California. The firm is deeply focused on investing in early-stage, seed, and Series A companies, specifically in sectors driving humanity toward technological advancement. These include space technology, robotics, AI, automation, and nanotechnology, with a mission inspired by the Kardashev Scale to help humanity progress toward a Type I civilization. Type One Ventures backs transformative companies such as Gravitics and Lunar Outpost, both leaders in space exploration and infrastructure. They also invest in groundbreaking ventures across diverse fields, including human longevity and the future of mobility. The firm typically takes a hands-on approach, offering not just capital but strategic guidance, leveraging a team of founders, operational experts, and technologists to support the long-term success of their portfolio. With investments ranging from space tech to human health and automation, Type One Ventures actively seeks visionary founders who are solving complex, high-impact problems. Their geographic focus is global, particularly in the U.S. and Europe, and they often co-invest with other major firms in the deep tech and space industries. Key members of the team include founding partner Tarek Waked and general partner Abdo John Hajj, both of whom drive the firm’s forward-looking investment strategy.

Übermorgen Ventures, founded in 2019 and based in Zurich, Switzerland, is a venture capital firm dedicated to tackling climate change through early-stage investments in climate tech startups. The firm focuses on high-impact sectors such as clean energy, carbon capture, sustainable agriculture, and green transportation. Their mission is to turn climate change mitigation into a massive business opportunity while generating strong financial returns. Übermorgen Ventures is particularly interested in startups that have the potential to significantly reduce greenhouse gas emissions. Their investment approach emphasizes patient capital, allowing startups to focus on long-term growth and environmental impact. They aim to generate measurable outcomes, targeting a reduction of over 1 million tons of CO2 equivalent annually across their portfolio within the next decade. The firm has built a diverse portfolio of 43 companies, including Open Forest Protocol, Fermify, and Companion.energy, each bringing innovative solutions to sustainability challenges. Übermorgen Ventures also works closely with startups to help them secure follow-on funding, providing strategic support throughout the journey from seed to scaling. The core team is led by experienced entrepreneurs such as Adrian Bührer and Myke Näf, who bring decades of experience in both business and investment. Their hands-on approach and focus on double impact (financial and environmental) make Übermorgen a key player in the European climate-tech space, positioning itself to make a meaningful difference in the fight against climate change.

The UCL Technology Fund (UCLTF) is a venture capital fund established in 2016 to commercialize cutting-edge research originating from University College London (UCL). Managed in partnership with AlbionVC and UCL Business, the fund focuses on investing in intellectual property arising from UCL's research in life sciences, physical sciences, and engineering. UCLTF plays a pivotal role in taking groundbreaking technologies from early-stage proof of concept through to commercialization, either via licensing or by forming spinout companies. With an emphasis on life sciences, the fund supports pioneering projects in areas such as gene therapy, oncology, and advanced materials. Notable investments include Orchard Therapeutics, a spinout specializing in rare disease gene therapies, and Bloomsbury AI, which developed natural language processing technology before being acquired by Facebook in 2018. The fund's portfolio is diverse, encompassing companies tackling global challenges like clean energy through firms such as Carbon Re, which is focused on decarbonizing heavy industries​. The fund’s mission is not only to support UCL's world-class academic research but also to deliver societal impact and substantial commercial returns. The first fund has seen impressive successes, including two Nasdaq IPOs and raising over £1 billion in external funding across its portfolio. Recently, UCLTF closed its second fund at £100 million, further strengthening its ability to back high-impact innovations in biotech, healthcare, and AI.

Ulu Ventures, based in Palo Alto, is a leading seed-stage venture capital firm with strong ties to Stanford and Silicon Valley. They focus on funding diverse entrepreneurial teams, particularly those led by women and minority founders. Ulu Ventures has made over 200 investments, with notable exits including Proterra, Taulia, and Blue River Technology​​. Their investment strategy is data-driven, aiming to reduce cognitive biases and systematically identify key drivers of risk and uncertainty. They invest in sectors such as enterprise IT, EdTech, FinTech, healthcare, and sustainability​ (Ulu Ventures)​. With an emphasis on diversity, 76% of their funded companies have diverse founders​​. The firm is co-founded by Miriam Rivera and Clint Korver, who bring extensive experience in entrepreneurship and venture capital. Ulu Ventures is recognized for its thoughtful and rigorous approach to venture funding, which has resulted in a portfolio that includes companies like Guild Education, Genesis Therapeutics, and Lex Machina​

Uncommon Capital, founded in 2014, is a venture capital firm that focuses on early-stage investments from pre-seed to Series A rounds. The firm is based in San Francisco and has a strong emphasis on software companies, particularly in sectors like B2B SaaS, marketplaces, consumer non-social, developer tools, and fintech. Uncommon Capital has a diverse portfolio with notable investments in companies such as Razorpay, a leading payment processing solution provider; Talkdesk, a cloud-based contact center software; and Function of Beauty, an internet-first brand offering customized skincare and haircare products. The firm also boasts investments in emerging companies like Morf Health, a health tech startup, and Antares Industries, focusing on environmental technology. The firm is led by experienced partners, including Tikhon Bernstam, co-founder of Scribd and Parse, and Jamie Quint, a seasoned product growth practitioner who has consulted for companies like Twitch, Everlane, and Substack​. Uncommon Capital distinguishes itself by providing hands-on operational support to its portfolio companies, helping them with product development, data infrastructure, marketing strategies, and engineering hiring.

Uncork Capital, founded in 2004 and based in San Francisco, is a prominent seed-stage venture capital firm known for its investments in early-stage startups across various sectors including SaaS, consumer marketplaces, hardware, and emerging technologies. Some of their most notable investments include Postmates, Fitbit, Eventbrite, and SendGrid. The firm's investment strategy revolves around backing visionary founders at the seed stage with typical check sizes ranging from $500,000 to $2 million. Uncork Capital manages over $900 million in assets through its Seed Fund (Uncork VII) and Opportunity Fund (Uncork Plus III), designed to support portfolio companies as they mature and scale. Led by Jeff Clavier, the founder and managing partner, the team includes partners like Andy McLoughlin, Susan Liu, and Amy Saper, all based in San Francisco. The team is known for its deep industry expertise and hands-on approach, providing strategic support and resources to help startups grow. Startups seeking investment from Uncork Capital should highlight strong product-market fit and innovative solutions with the potential for significant market impact. The firm values clear, compelling pitches and prefers introductions through its extensive network​.

Uncorrelated Ventures, headquartered in San Francisco, specializes in early-stage investments in infrastructure software, decentralized finance, and fintech sectors. Founded by Salil Deshpande in 2019, the firm has a portfolio that includes companies like Tandem PV, HockeyStack, and Bodo.ai. They typically engage in Seed and Series A rounds, with an average check size of $17M. The fund is known for its hands-on approach, offering strategic support and leveraging a robust network to help startups scale. Uncorrelated Ventures values clear, innovative pitches that demonstrate significant market potential and technological advancement. Key team members include founder Salil Deshpande, a veteran in the venture capital space, and a dedicated team with diverse expertise in technology and investment management. Startups can approach Uncorrelated Ventures through their extensive network or direct outreach, emphasizing the unique aspects of their technology and market approach.

Underdog Labs is a pre-seed venture capital firm based in Sebastopol, California, with a focus on supporting early-stage founders as they navigate the critical first milestones of their startups. Founded by Alex Chang and David Hehman in 2019, the firm specializes in working with passionate entrepreneurs who have promising ideas but need guidance and capital to turn these into scalable businesses. Underdog Labs targets very early-stage companies, often being the first institutional investors after initial angel rounds. The firm is industry-agnostic, but it has a strong focus on sectors like artificial intelligence, SaaS, fintech, health tech, and consumer products. With a hands-on approach, Underdog Labs provides not just capital but also strategic mentorship, leveraging the extensive entrepreneurial experience of its founders to help startups achieve product-market fit and scale effectively. The firm typically invests between $100K and $500K per company and has built a diverse portfolio of startups across various industries. Underdog Labs is particularly known for its commitment to backing underrepresented founders, further cementing its role as a key player in the early-stage venture ecosystem.

Underscore.VC, established in 2015, is a Boston-based venture capital firm dedicated to early-stage B2B software startups. With a strong emphasis on community, Underscore integrates a unique Core Community of experienced entrepreneurs and industry leaders who actively support portfolio companies. This approach ensures founders receive comprehensive guidance and resources tailored to their specific needs​. Notable investments by Underscore.VC include companies such as Project44, Salsify, Slang, Soofa, and TetraScience, showcasing their focus on B2B fintech, vertical SaaS, and emerging technologies​. The firm primarily invests in pre-seed and seed rounds, typically leading these rounds and committing substantial support beyond just financial backing. Their strategy is rooted in building strong, collaborative relationships with founders, emphasizing a partnership approach rather than just a financial transaction. They value transparency, long-term vision, and active involvement in the companies they support. This philosophy is reflected in their careful selection process and active participation in the growth and scaling of their investments​. For startups looking to engage with Underscore.VC, it's beneficial to demonstrate a strong alignment with their community-driven values and a clear, innovative vision for their business model. Approaching them with a well-thought-out plan and readiness to leverage their extensive network can significantly enhance the chances of forming a successful partnership.

Union Labs, founded in 2018 and based in San Mateo, California, is a deep-tech venture capital firm focusing on pre-seed and seed-stage investments. Co-founded by Nate Williams and Chris Kim, Union Labs primarily invests in startups tackling big challenges across sectors like robotics, AI/ML, IoT, and smart infrastructure. The firm aims to solve complex global problems through innovative technology, often working directly with founders to de-risk the journey to product-market fit. Union Labs has made 28 investments, with notable companies like Pico MES, which develops factory operations software, and Urban Machine, focusing on forestry processing. The firm incubates many of its companies, having initially grown out of Kleiner Perkins with backing from Google Ventures, allowing it to offer both financial and hands-on operational support. This approach ensures that its startups benefit from Union Labs' extensive network and expertise. Union Labs is committed to advancing deep-tech solutions that contribute to a smarter, more connected world.

Union Square Ventures (USV), a venture capital firm based in New York City, focuses on investing in early-stage technology startups. Their investment philosophy is centered on finding companies at the edge of large markets being transformed by technological and societal pressures. USV looks for new behaviors and business models enabled by technology, rapid experimentation, and broadening access to resources and opportunities. USV’s portfolio includes a range of notable companies such as Twitter, Etsy, MongoDB, and Twilio. They have invested across various sectors including social media, marketplaces, developer tools, health, fintech, web3, and climate tech. Their approach involves maintaining relatively small fund sizes and collaborating closely as a team to make investment decisions and support portfolio companies.

Uniseed is Australia's longest-running venture capital fund, established in 2000, with a strong focus on commercializing innovative research from its partner universities and research institutions. These include leading institutions like the University of Queensland, the University of Melbourne, and Monash University, among others. Uniseed supports startups in various sectors such as biotechnology, quantum computing, pharmaceuticals, and green energy. As a seed-stage investor, Uniseed helps researchers turn their ideas into marketable products by offering seed capital, expert guidance, and access to an extensive network of industry professionals. The firm has overseen more than 60 startups and over 12 successful exits, including notable deals like the sale of Spinifex Pharmaceuticals to Novartis and Fibrotech to Shire. In partnership with UniSuper, Uniseed manages significant capital to support deep-tech startups aiming for global impact. Uniseed’s latest $75 million commitment ensures its continued support for emerging technologies, and with its growing network of academic and institutional partners, the fund is poised to lead more groundbreaking innovations to market.

E14 Fund is an MIT-affiliated venture capital firm focused on supporting deep-tech startups emerging from the MIT community. Established in 2013 and rooted in the MIT Media Lab, the fund specializes in companies that are addressing critical global challenges through breakthrough science and engineering. E14 Fund invests in early-stage startups, typically from pre-seed to Series A, with a focus on industries such as robotics, artificial intelligence, quantum computing, and synthetic biology. Some notable investments include Formlabs, a leader in 3D printing technology, and Overjet, a pioneer in AI-powered dental care solutions. The fund is more than just a capital provider; it acts as a strategic partner, helping founders transition from academic research to building scalable businesses. E14 leverages the vast MIT network to connect entrepreneurs with industry leaders, mentors, and technical resources that can help accelerate their growth. A significant portion of the firm’s profits is reinvested into MIT, highlighting its commitment to fostering long-term innovation within the university ecosystem. Led by managing partners Calvin Chin and Habib Haddad, E14 Fund works closely with founders to address both scientific and business challenges, providing hands-on support throughout their journey. The fund’s portfolio companies typically possess unique intellectual property and a clear path to market dominance, reflecting E14’s focus on ventures with transformative potential. By supporting startups from their earliest stages, E14 Fund plays a crucial role in translating groundbreaking MIT research into impactful, market-ready technologies.

Unpopular Ventures is a venture capital firm founded by Peter Livingston, focusing on early-stage tech startups that are often overlooked by mainstream investors. They have invested in over 300 startups globally, with a portfolio spanning various industries and regions. Notable investments include Jeeves, a global business banking platform, Farcana, a battle royale shooter game, and Foundation Devices, developers of Bitcoin-centric tools. The firm's strategy is to find and invest in unconventional opportunities that have the potential for significant impact and growth. They emphasize global investments, particularly in emerging markets, driven by Livingston's own experience living and working around the world. This global perspective allows them to identify and support startups that are off the beaten path but have strong growth potential​. Unpopular Ventures operates both as a syndicate and a rolling fund on AngelList, providing flexible investment options to their backers. The firm's unique approach and diverse portfolio have made it a significant player in the venture capital landscape, despite its name.

Unshackled Ventures, founded in 2014 and headquartered in San Francisco, California, is a venture capital firm dedicated to supporting immigrant entrepreneurs. The firm focuses on early-stage investments, particularly in technology and innovation sectors. Unshackled Ventures aims to provide not only capital but also visa support, enabling immigrant founders to build successful companies in the U.S. Their investment portfolio includes a diverse array of companies. Notable investments include Lily AI, which uses AI to improve retail personalization, and Pod Foods, a B2B marketplace for food brands and retailers. Other significant companies in their portfolio are Plantible Foods, a sustainable food company, and Career Karma, a platform helping people find jobs through bootcamps. Unshackled Ventures has made a total of 86 investments and has seen 17 exits, highlighting their effectiveness in nurturing startups to maturity. Their approach involves investing at the very earliest stages, often at "day zero," to help founders navigate the complexities of building a business from the ground up. The team is led by co-founders Nitin Pachisia and Manan Mehta, who are committed to leveraging their own experiences as immigrants to support other immigrant founders. Their mission is to unlock the potential of these entrepreneurs by providing the necessary resources, guidance, and community support to achieve their visions.

Untapped Capital is a venture capital firm based in Bellevue, Washington, founded in 2020 by Jessica Jackley and Yohei Nakajima. The firm focuses on pre-seed investments, targeting unexpected and often overlooked founders who are pioneering the latest technologies to build a more abundant future. Untapped Capital operates as a generalist VC, meaning they do not limit themselves to specific industries but instead invest across a broad spectrum, with a particular interest in companies driving innovation in climate tech, healthcare, and productivity software. The firm is known for its hands-on approach, running itself much like a startup to better understand and support the challenges faced by the founders they back. Untapped Capital has made 36 investments to date, with notable companies in their portfolio including Covalent, a leader in climate tech, and Mars Materials, which focuses on sustainable environmental solutions. Their investment strategy is centered around early-stage companies, often being one of the first institutional investors to commit capital. The team at Untapped Capital leverages their deep expertise and network to provide strategic guidance, helping their portfolio companies scale effectively. They have also developed a reputation for integrating cutting-edge AI tools and methodologies to enhance the growth and development of the startups they support. This innovative approach has made Untapped Capital a distinctive player in the venture capital landscape, particularly in supporting founders who might otherwise be overlooked by traditional VCs​.

Unusual Ventures is a seed-stage venture capital firm founded in 2018 by John Vrionis and Jyoti Bansal. They focus on providing hands-on support to early-stage startups in sectors like infrastructure software, SaaS, fintech, and consumer applications. Notable investments include Arctic Wolf Networks, Carta, Robinhood, Harness, and Vivun. Unusual Ventures differentiates itself by embedding experienced operators with startups, offering deep operational support in areas such as marketing, sales, and recruiting. This approach helps founders navigate the challenging early stages of their business, working closely to find product-market fit and build a strong foundation for future growth. Their engagement model is designed to provide comprehensive support, acting as interim executives to ensure startups have the resources they need to succeed. The firm also emphasizes diversity and social impact, partnering with institutions that are positive forces in education, healthcare, and the arts. This mission-driven approach ensures that the returns generated contribute to meaningful progress. With offices in Menlo Park, San Francisco, and Boston, Unusual Ventures has raised multiple funds, including their recent $485 million Fund III, bringing their total assets under management to over $1 billion. This commitment underscores their dedication to supporting seed-stage founders with unparalleled resources and expertise.

UOB Venture Management (UOBVM), a subsidiary of United Overseas Bank (UOB), was established in 1992 and focuses on venture capital and private equity investments, primarily in Southeast Asia, Greater China, and the United States. The firm targets growth-stage companies across various sectors, including healthcare, advanced manufacturing, consumer services, and digital economy ventures. UOBVM is known for integrating ESG principles and impact investing into its strategy, as demonstrated by its Asia Impact Investment Fund series. UOBVM has a significant portfolio with over 164 investments, and some notable exits include Gojek and Nanosys. They emphasize supporting businesses that contribute to sustainable development and innovation, particularly those improving livelihoods in the region. The firm manages several funds, including the ASEAN China Investment Fund and Asia Impact Investment Fund II, which raised over $60 million for initiatives in underserved markets​. The firm's leadership includes CEO Kian-Wee Seah, with key members like Mark Yeo and Jean Thoh, all based in Singapore, where the company is headquartered.

UP.Partners is a venture capital firm dedicated to transforming the mobility sector. Headquartered in Santa Monica, California, UP.Partners focuses on investing in groundbreaking technologies that improve the movement of people and goods. The firm targets early-stage ventures in various mobility sectors, including air, land, sea, and space. The fund's strategy emphasizes investment in enabling technologies, such as software for precise positioning, electric vertical takeoff and landing (eVTOL) aircraft, and sustainable aviation fuels. UP.Partners' notable investments include Skydio, a leader in flight autonomy; Beta Technologies, which develops eVTOL aircraft; and UnitX, a manufacturing quality assurance platform. UP.Partners manages a $230 million venture fund and collaborates with major corporations like Alaska Airlines, ARK Invest, and Woven Capital, the investment arm of Toyota's Woven Planet Group. The firm also hosts the annual UP.Summit, a pivotal event for the mobility community, bringing together entrepreneurs, investors, and industry leaders to drive innovation in transportation. The firm was co-founded by aviation and technology entrepreneurs Ben Marcus and Cyrus Sigari, along with Adam Grosser, a veteran investor with a strong background in climate-focused companies. They are supported by a team of experts, including Ally Warson and industry leaders like Brian McClendon and Eric Hirshberg. UP.Partners seeks out bold entrepreneurs with innovative ideas that can transform mobility, aiming to make transportation cleaner, faster, safer, and more cost-effective. The firm provides not only capital but also strategic partnerships and resources to help startups scale effectively.

UP2398 is an early-stage venture capital firm based in Redwood City, California, established in 2015 by Alexander Poon, Randy Ching, and Pierre Omidyar. Specializing in pre-Series A investments, the firm focuses on high-growth sectors including artificial intelligence, blockchain, SaaS, and high-tech industries. The firm has a diverse portfolio of 34 investments, including standout companies such as Standard Fleet, MakerDojo, and Slapdash. UP2398 often targets companies that leverage technology to disrupt traditional sectors, from automotive software and AI-driven analytics to consumer technologies and e-commerce platforms. UP2398’s strategy involves providing early-stage capital and hands-on support to foster innovation and help startups scale rapidly. The firm co-invests with leading venture capital firms like SV Angel, Soma Capital, and Intel Capital, emphasizing a collaborative approach to venture investing. In addition to its focus on cutting-edge technology, UP2398 has supported companies in industries such as renewable energy, IoT, and machine learning, helping them navigate early growth stages and achieve successful exits. The firm has successfully guided multiple companies to acquisition or scaling, with notable exits including Convex and INDUS.AI. With its team’s deep experience in entrepreneurship and venture capital, UP2398 continues to identify and support companies that are transforming their industries. By focusing on sectors with high innovation potential, UP2398 remains a prominent player in the early-stage investment landscape, helping to fuel the next wave of technological breakthroughs.

Upfront Ventures, founded in 1996 and based in Santa Monica, California, is a prominent venture capital firm focused on early-stage technology investments. With over $2 billion in total funds raised, the firm has supported more than 200 companies across various sectors, including digital media, SaaS, consumer internet, and retail innovation. Notable investments include well-known companies like PayPal Credit, thredUP, Apeel Sciences, and Ulta. The firm's investment strategy typically involves leading seed and Series A rounds, providing not just capital but also strategic guidance and resources to help startups scale. They have a strong presence in the Los Angeles tech ecosystem, contributing to the growth of Silicon Beach. Upfront Ventures is also known for hosting the annual Upfront Summit, a major tech conference in Los Angeles that gathers industry leaders and innovators. Led by managing partners Yves Sisteron and Mark Suster, Upfront Ventures combines extensive industry experience with a commitment to transparency and long-term partnership with entrepreneurs. Their investments are global, with a focus on leveraging their strategic location in Los Angeles to support the thriving local startup scene. For startups looking to engage with Upfront Ventures, a clear demonstration of innovative solutions and strong market potential is key. The firm values introductions through its network and prefers pitches that align with its investment focus and ethos​.

Upheaval Investments is a venture capital firm based in Chicago, focused on early-stage investments in disruptive technologies. The firm actively seeks out companies that are leveraging innovative solutions to tackle fundamental problems, particularly within the technology, healthcare, and industrial sectors. They invest globally, supporting startups from pre-seed through Series A rounds. The fund's approach is characterized by a commitment to partnering closely with entrepreneurs to accelerate growth and build impactful businesses. Their portfolio spans a diverse array of sectors, including AI, cleantech, robotics, and autonomous vehicles. Upheaval Investments is led by Riley Florsheim, who emphasizes a hands-on approach to fostering innovation and guiding companies from their earliest stages. While specific portfolio companies are not widely publicized, the firm's strategy revolves around identifying visionary founders with the potential to drive significant change across industries.

UpHonest Capital, founded in 2015 and based in Santa Clara, California, is a venture capital firm focused on early-stage investments. They invest across various sectors, including consumer, enterprise, deep technology, and web 3.0, supporting companies from Seed to Series A stages. The firm has built a substantial portfolio, investing in over 400 companies, with 28 unicorns and 23 exits via M&A or IPO. Notable investments from UpHonest Capital include companies such as Checkr, an AI-based platform for employee background verification; Hims & Hers, a telehealth service; Rippling, a human capital management software; and Instacart, a leading online grocery platform. Other significant investments include Turing AI, Golden, and Substack. UpHonest Capital is known for its sector-agnostic approach and its active support for portfolio companies, often co-investing with major firms like Sequoia, Accel, and Andreessen Horowitz. The firm also emphasizes building a vibrant ecosystem for entrepreneurs and investors through initiatives like the UpHonest Scouts and Beta Fellowship programs.

Upside Partnership, founded by Kent Goldman in San Francisco, is a seed and pre-seed venture capital firm known for its early-stage investments in technology and software sectors. Some notable companies in their portfolio include Hims & Hers, Allbirds, and Life360, highlighting their ability to identify high-growth potential startups. Upside Partnership is industry-agnostic, focusing on purpose-built teams and companies with a strong vision and operational efficiency. They invest primarily in the U.S. market, often being the first institutional investor to commit, which allows them to shape the initial growth trajectory of their portfolio companies. Their strategy involves writing initial checks of around $500K, with 70% of their fund reserved for supporting founders in subsequent rounds. They place a high value on long-term partnerships and are known for their hands-on approach, guiding startups through their growth phases with a combination of mentorship and strategic advice. Kent Goldman, previously a partner at First Round Capital, brings extensive experience in early-stage investing. Christina Hunt, another key partner, has a strong background in both startup operations and venture capital, ensuring that Upside Partnership provides comprehensive support to its founders. This blend of expertise and a founder-first philosophy makes Upside Partnership a distinguished player in the venture capital space.

UpWest, a Silicon Valley-based seed fund, focuses on investing in Israel’s most promising entrepreneurs targeting the US market. Founded in 2012, UpWest has made over 111 investments and facilitated 21 successful exits. The firm emphasizes early-stage investments, typically participating in pre-seed, seed, and Series A funding rounds​. UpWest's portfolio includes companies across various sectors such as AI, machine learning, proptech, fintech, cybersecurity, and SaaS. Notable investments include SentinelOne, which specializes in endpoint security software, HoneyBook, a project management tool, and CyCognito, a company focusing on uncovering and eliminating IT risks​​. The firm is led by founding partners Shuly Galili and Gil Ben-Artzy, who bring extensive experience and a strong network to support Israeli founders. UpWest has helped its portfolio companies raise over $3 billion in follow-on investments, underscoring its commitment to fostering growth and innovation.

Urban Innovation Fund, founded in 2016 and based in San Francisco, focuses on investing in early-stage companies that enhance the livability, sustainability, and economic vitality of cities. The fund supports startups at the pre-seed and seed stages across various sectors including transportation, climate tech, proptech, edtech, fintech, public health, civic tech, and food systems. Notable investments include Electriphi, a software company for electric fleet management acquired by Ford, and codeSpark, an educational platform teaching kids to code, which was acquired by BEGiN. Other significant investments are BookNook, a tutoring platform for improving reading skills, and Jeeves, a global payment network for small businesses that has recently seen its valuation rise to $2.1 billion. The fund, co-founded by Clara Brenner and Julie Lein, provides not only capital but also regulatory support to help entrepreneurs navigate complex urban challenges. Their portfolio reflects a commitment to tackling key issues facing urban areas today, from sustainable finance to community health.

V1.VC is a venture capital firm based in Boulder, Colorado, founded in 2015. The firm specializes in early-stage investments in internet, B2B software, consumer, financial, crypto, and deep tech companies across North America. V1.VC focuses on being patient, long-term capital partners for ambitious founders, leveraging their experience as current and former operators to support startups from initial stages to successful exits. Co-founded by Brett Jackson and Benny Joseph, V1.VC aims to be the most supportive investor in a founder’s journey. Brett Jackson brings extensive experience from roles at AVX Aircraft and Crocs, while Benny Joseph is known for his tenure as CTO at Allbirds and his role in founding GoodApril, which was acquired by Intuit. V1.VC has a diverse portfolio that includes notable companies like Allbirds, DoorDash, and OpenSea. They have made over 86 investments and have achieved 27 exits. The firm is dedicated to helping startups navigate the critical early stages of development and scale successfully. The team at V1.VC emphasizes a collaborative approach, working closely with startups to provide strategic guidance, resources, and connections to ensure their growth and success in the competitive market.

Valar Ventures, co-founded by Peter Thiel, Andrew McCormack, and James Fitzgerald, has made a significant mark in the venture capital world by focusing on fintech startups with a global reach. Notable investments include Wise, Xero, Petal, N26, and Stash, highlighting their commitment to backing transformative financial technology companies. These investments demonstrate Valar's ability to identify and nurture groundbreaking startups. The firm primarily invests in early-stage companies, often leading funding rounds with checks ranging from $1M to $10M. Their geographic focus spans North America and Europe, allowing them to tap into diverse markets and innovative ecosystems. This strategic approach ensures they are well-positioned to support startups poised for international growth. Valar Ventures operates with a clear investment strategy: they seek out companies with innovative fintech solutions that have the potential to disrupt traditional financial services. They are known for their hands-on approach, providing not just capital but also strategic guidance to help their portfolio companies scale effectively. The team, based in New York, brings deep fintech expertise and a strong network, which is invaluable to the startups they invest in. Founders looking to partner with Valar should present a clear, innovative fintech proposition with a strong potential for transformative impact. Valar Ventures is particularly interested in businesses that can demonstrate a solid growth trajectory and a compelling vision for the future of finance.

Valia Ventures is an early-stage venture capital firm that invests in bold and innovative startups across various sectors including fintech, healthcare, consumer, and enterprise software. Based in New York, San Francisco, and London, the firm focuses on pre-seed, seed, and Series A investments, with check sizes ranging from $50,000 to $1 million. Valia Ventures also has an Opportunity Fund for investing in mature companies at the Series B stage and beyond. The firm is led by Managing Partner Khaled Jalanbo, along with a team of experienced investors like Riley Rodgers and Omar Sebai. They aim to be long-term partners, supporting companies throughout their growth stages with both capital and strategic guidance​. Valia Ventures has made significant investments in companies such as Selfbook, Humane, and Legacy, demonstrating their commitment to backing transformative ideas. Their portfolio is diverse, encompassing sectors from fintech and healthcare to enterprise software​.

Valley Capital Partners is a Silicon Valley-based venture capital firm founded in 2013, specializing in early-stage investments. The firm has a strong focus on Seed and Series A funding, particularly in enterprise technology sectors like AI/ML infrastructure, cybersecurity, and network infrastructure. Known for its hands-on approach, Valley Capital Partners works closely with founders, helping them build solid foundations for rapid growth through governance, talent recruitment, and strategic enterprise partnerships. Valley Capital’s investment strategy is marked by high conviction and concentrated bets, typically making 8-12 core investments per fund. Their network of exceptional Limited Partners (LPs), including top-tier tech investors, provides startups with unique access to insights and co-investment opportunities. Recent notable exits include Yubico and Affirm, highlighting the firm’s strength in nurturing high-growth companies. Led by seasoned professionals like Stephen O’Hara and Mitchell Kokko, the firm takes a long-term partnership approach, aiming to stay deeply involved with its portfolio companies. Unlike many VCs, Valley Capital avoids spreading itself thin across too many deals, choosing instead to focus on fewer, high-impact investments that enable deeper collaboration with founders. Based in Menlo Park, California, Valley Capital continues to back innovators, leveraging its deep Silicon Valley roots to fuel the next generation of enterprise tech success.

Valo Ventures is a thesis-driven venture capital firm based in Palo Alto, California, that invests in companies addressing global challenges such as climate change, resource scarcity, and inequality. The firm focuses on three main areas: digitization, decarbonization, and adaptation. Valo Ventures targets early to growth-stage companies in North America and Europe, seeking to create a positive environmental and social impact while generating competitive financial returns. Their portfolio includes companies like XGS Energy, ARRIS, and Boston Materials, which leverage advanced technologies to tackle significant issues such as renewable energy, sustainable materials, and carbon reduction​​. Valo Ventures prides itself on fostering partnerships based on trust, reciprocity, and shared values, emphasizing the importance of diversity and long-term impact.

Valor Capital Group, founded in 2011, is a cross-border venture capital firm that focuses on bridging the US, Brazilian, and Latin American tech markets. Headquartered in New York, with significant operations in São Paulo, Valor Capital Group invests across various stages from seed to growth. Their portfolio spans multiple sectors, including fintech, B2B, consumer services, and technology. Some of Valor Capital Group's notable investments include companies like Nextdoor, Rubicon, and Satellogic. They have had a number of successful exits, with companies such as Udacity and Bitso achieving significant milestones. Valor Capital Group is known for supporting innovative startups like CloudWalk, which has achieved centaur status with over $300 million in annual recurring revenue, and Loft, valued at $2.9 billion as of April 2021. The firm’s team includes co-founders Clifford Sobel and Scott Sobel, with key partners like Michael Nicklas and Carlos Costa. They bring a wealth of experience and a robust network to their investment strategy, focusing on driving local innovation through global insights. Valor Capital Group’s unique cross-border approach and extensive portfolio underscore their commitment to fostering growth and innovation in emerging markets, particularly within the tech ecosystem of Brazil and Latin America.

Valor Equity Partners, founded in 1995 and based in Chicago, is a leading private equity firm specializing in operational growth investments. The firm strategically invests across various stages of company development, with a keen focus on technology sectors. Valor Equity Partners is renowned for its hands-on approach, working closely with portfolio companies to enhance growth and scalability. The firm's notable investments include SpaceX, a pioneer in aerospace; Gopuff, an on-demand convenience delivery service; Misfits Market, a direct-to-consumer grocery delivery provider; and Zipline, a company revolutionizing autonomous drone delivery systems. Valor's investment strategy emphasizes providing strategic and operational support, ensuring that portfolio companies can achieve substantial growth. Valor Equity Partners manages multiple funds, with their recent Fund V closing at $1.7 billion, underscoring their strong position in the private equity market. The firm's ability to attract significant capital commitments highlights investor confidence in their strategic approach and track record of success. Key team members include founder and CEO Antonio Gracias, who brings extensive experience and leadership to the firm. Valor's team is known for its deep industry knowledge and commitment to driving operational excellence within their portfolio companies. This combination of strategic investment and operational support positions Valor Equity Partners as a pivotal player in fostering innovation and growth within the technology sector.